In this post we will focus on the mast cell-glia (microglia, astrocyte, oligodendrocyte) interaction with our body and how they contribute to chronic inflammatory diseases such as CIRS and SALI.Read More
Catuaba is a powerful plant that can improve depression, anxiety, fatigue, and more.
In this post, we will discuss the different forms of Catuaba (true vs non-true catuabas), the benefits of catuaba, and dosage of catuaba.Read More
Recent evidence suggests that 70–90% of chronic disease is likely related to environmental determinants.
In this post, we will discuss how biotoxin accumulation may cause chronic illness.Read More
In this post, we will discuss Homer proteins (mainly homer1), their implicated diseases with dysregulation, and some novel ways to help with homeostasis.Read More
Paraoxonase 1 (PON1) is an enzyme that plays a role in most diseases.
In this post, we will discuss how you can use PON1 to improve overall health, longevity, and detox mechanisms.Read More
The term Humanin (HN) was coined by its discoverer, Professor Nishimoto, to denote the potential of this molecule to restore the “humanity” of patients with Alzheimer’s disease.
Later we have found humanin protects cells from oxidative stress, serum starvation, hypoxia, and other insults as well as also improves cardiovascular disease and Alzheimer's disease.Read More
Protein deglycase DJ-1 (DJ-1), also known as Parkinson disease protein 7 (PARK7) is a master regulator of redox status.
In this post, we will discuss how DJ-1 increases dopamine, enhances mitochondria, and combats most oxidative-stress related diseases.Read More
Recent data suggests that chronically low levels of circulating LPS may be associated with the development of metabolic diseases such as insulin resistance, type 2 diabetes, atherosclerosis and cardiovascular disease. R
In this post, we will discuss how LPS affects the body and how to reverse endotoxemia.Read More
Dopamine is extremely important for everyday function and plays a much larger role in the body than just bonding, motivation, cognition, emotion, well-being, and movement.
Unfortunately, our environment today is very good at manipulating and hijacking our dopamine system.
In this post we will discuss, how/why dopamine is produced, how chronic inflammation affects dopamine, what are some quick fixes for dopamine, and what are some long lasting dopamine builders, as well how to avoid losing dopamine.Read More
Recent cancer research has helped us understand how the body detoxes.
By studying upregulated genes in tumorous cells, we were able to find the Nuclear Erythroid 2–Related Factor 2 (NRF2) pathway.
NRF2 is a major transcription factor in detoxing the body and keeping it healthy.
In this post, we will discuss the benefits/downsides of NRF2 activation, as well as why NRF2 may be hurting you more than helping you (and what you can do about it).Read More
Controlling Excitatory Amino Acid Transporters (EAATs) activity is a novel way to reduce excitotoxicity (neuronal damage due to overactivity) in the brainRead More
I usually advise to stay away from all antibiotics, but I've had clients that have had profoundly beneficial experiences with certain beta-lactam antibioticsRead More
Since the late 1970s, the use of glyphosate-based herbicides (GBHs) has increased approximately 100-fold.
Glyphosate is the active ingredient in Roundup®.
In this post, we will discuss glyphosate's toxic effects (even at extremely low doses).Read More
Nogo-A is one of the most potent growth inhibitors in the central nervous system.
It is involved in creating new blood cells, developing new stem cells, protecting growth of cancer, and modulating the immune system.
It is highly expressed after adolescent development, traumatic brain injuries, and many myelin-related diseases.Read More
Interleukin 8 (IL8 or CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells.
IL-8, also known as neutrophil chemotactic factor, has two primary functions:
It induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection.
It also induces phagocytosis once they have arrived.
Medical marijuana and legalization have been a hot topics recently. I wanted to cover the plethora of benefits of the endocannabinoid system.
Disclaimer: I made sure to only work on this post while vaping CBD.Read More
Ciliary neurotrophic factor (CNTF) is a neurotrophic factor with promising benefits in a wide range of pathologies such asneurodegenerative diseases, spinal cord injuries, retinal degeneration, autoimmune neuroinflammation and obesity-related metabolic diseases.