How Ciguatoxins Cause CIRS, Brain Fog, & Loss of NAD+

Ciguatoxins are a harmful byproduct of marine life and their exposure can cause both acute and chronic long term neurological effects.

In this post, we will discuss how ciguatoxins can cause CIRS, brain fog, and loss of NAD+.

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31+ Ways To Combat And Fix Tinnitus (With Mechanisms)

In this post, we will discuss underlying mechanisms and pathologies of tinnitus, genetic predispositions, and effective ways to combat tinnitus.

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All About Histamine H3 Receptors (HRH3/HR3): Genetics, Mechanisms, And Antagonists

Is histamine a villain… or really a superhero?

It really depends on which receptor it works on and where it is in the body.

In this post, we will discuss how to use the 3rd histamine receptor to boost cognition, memory, and attention.

We will first discuss how the histamine receptors work.

Then, we will move onto the benefits (and downsides) of blocking Histamine H3 Receptor's (HRH3 or H3R) activity with natural and pharmacological methods.

Lastly, we will discuss the potential benefits of increasing HRH3 with some agonists, HRH3's mechanism of action, and some important HRH3 SNPs.

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HOMER1, HOMER2, and HOMER3: How These Homologs Promote Strong Synaptic Plasticity

In this post, we will discuss Homer proteins (mainly homer1), their implicated diseases with dysregulation, and some novel ways to help with homeostasis.

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The Role of DARPP-32 In Addiction, Schizophrenia & Parkinson's Disease

In this post, we will discuss how protein phosphatase 1 regulatory subunit 1B (PPP1R1B), also known as dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32) plays a large role addiction, Parkinson's Disease, schizophrenia, cognition, and cancer. 

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Balancing Excitatory Amino Acid Transporter Activity

Controlling Excitatory Amino Acid Transporters (EAATs) activity is a novel way to reduce excitotoxicity (neuronal damage due to overactivity) in the brain

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