In this post, we will discuss therapeutic and off-label effects of Cyproheptadine (Periactin), as well as side effects and mechanisms of this drug.Read More
Ciguatoxins are a harmful byproduct of marine life and their exposure can cause both acute and chronic long term neurological effects.
In this post, we will discuss how ciguatoxins can cause CIRS, brain fog, and loss of NAD+.Read More
Do you get the odd sensation of body buzzing like your body is moving when you are completely still?
The feeling could be when laying down at the end of the day, but it feels like something is either buzzing next to you or inside of you.
These are what I call Internal Tremors or Body Buzzing.
This is not primarily anxiety based, although the unknown cause of this odd phenomenon can trigger anxious feelings.Read More
Phoenixin is a peptide that regulates reproductive function, behavior, sensory perception, memory retention, cardiovascular health and food intake.Read More
In this post, we will discuss what parvalbumin is, how it plays a role in chronic illnesses, and what you can do to increase it.Read More
In this post we will discuss the downsides of uranium and proven/effective methods for protecting/removing uranium from the body.Read More
Robuvit and Oak Wood extracts from the Quercus species have shown to have very promising results in combating fatigue in human trials.
In the post, we will discuss the benefits of Quercus species and my experience with supplementing Robuvit.Read More
PeaLut is the combination of two powerful components that when combined can abolish inflammation, increase hippocampal growth, and reduce pain.
In this post, we will discuss the benefits of PeaLut and where to buy it.Read More
Embelin suppresses cancer, combats inflammation, ameliorates autoimmunity, and destroys many infectious agents.
It also has anti-diabetic, anti-obesity, neuroprotective, and cardioprotective protective effects.
In this post, we will discuss the MANY benefits of embelin, its natural sources, and some synergies of embelin.Read More
Suvorexant is a dual-orexin receptor antagonist that improves insomnia.Read More
Is histamine a villain… or really a superhero?
It really depends on which receptor it works on and where it is in the body.
In this post, we will discuss how to use the 3rd histamine receptor to boost cognition, memory, and attention.
We will first discuss how the histamine receptors work.
Then, we will move onto the benefits (and downsides) of blocking Histamine H3 Receptor's (HRH3 or H3R) activity with natural and pharmacological methods.
Lastly, we will discuss the potential benefits of increasing HRH3 with some agonists, HRH3's mechanism of action, and some important HRH3 SNPs.Read More
In this post, we will discuss Homer proteins (mainly homer1), their implicated diseases with dysregulation, and some novel ways to help with homeostasis.Read More
Unlike the current drugs approved for Alzheimer's Disease, J147 is neither an acetylcholinesterase inhibitor nor a phosphodiesterase inhibitor, yet it enhances cognition with a short-term treatment.
In this post, we will discuss how the curcumin derivative J147 improves memory and I'll explain a very powerful alternative way to get its benefits.Read More
Paraoxonase 1 (PON1) is an enzyme that plays a role in most diseases.
In this post, we will discuss how you can use PON1 to improve overall health, longevity, and detox mechanisms.Read More
The term Humanin (HN) was coined by its discoverer, Professor Nishimoto, to denote the potential of this molecule to restore the “humanity” of patients with Alzheimer’s disease.
Later we have found humanin protects cells from oxidative stress, serum starvation, hypoxia, and other insults as well as also improves cardiovascular disease and Alzheimer's disease.Read More
Recent data suggests that chronically low levels of circulating LPS may be associated with the development of metabolic diseases such as insulin resistance, type 2 diabetes, atherosclerosis and cardiovascular disease. R
In this post, we will discuss how LPS affects the body and how to reverse endotoxemia.Read More
When you optimize your body and fix all deficiencies, where is there to go next in enhancing your body?
Well there is hormesis, which is a very powerful tool for enhancing all aspects of your life.
Hormesis, if done properly can strengthen metabolism, longevity, and wellbeing as well as protect you from chronic illness in general.
In this post we will discus what hormesis is, how to do it, and what to watch out for so you can do it properly.Read More
In this post, we will discuss how protein phosphatase 1 regulatory subunit 1B (PPP1R1B), also known as dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32) plays a large role addiction, Parkinson's Disease, schizophrenia, cognition, and cancer.Read More
Dopamine is extremely important for everyday function and plays a much larger role in the body than just bonding, motivation, cognition, emotion, well-being, and movement.
Unfortunately, our environment today is very good at manipulating and hijacking our dopamine system.
In this post we will discuss, how/why dopamine is produced, how chronic inflammation affects dopamine, what are some quick fixes for dopamine, and what are some long lasting dopamine builders, as well how to avoid losing dopamine.Read More
Update to my life: I have damage to my caudate and putamen, two parts of the striatum that are responsible for dopamine neurotransmission and synthesis.
My caudate is small (atrophy) and my putamen is enlarged (inflamed).Read More