The 19+ Benefits Of Cyproheptadine (Periactin) With Side Effects And Mechanisms

In this post, we will discuss therapeutic and off-label effects of Cyproheptadine (Periactin), as well as side effects and mechanisms of this drug.

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How Ciguatoxins Cause CIRS, Brain Fog, & Loss of NAD+

Ciguatoxins are a harmful byproduct of marine life and their exposure can cause both acute and chronic long term neurological effects.

In this post, we will discuss how ciguatoxins can cause CIRS, brain fog, and loss of NAD+.

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Why Do I Get Body Buzzing And/Or Internal Tremors?

Do you get the odd sensation of body buzzing like your body is moving when you are completely still?

The feeling could be when laying down at the end of the day, but it feels like something is either buzzing next to you or inside of you.

These are what I call Internal Tremors or Body Buzzing.

This is not primarily anxiety based, although the unknown cause of this odd phenomenon can trigger anxious feelings. 

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All About Phoenixin: Pros And Cons Of Phoenixin And GPR173

Phoenixin is a peptide that regulates reproductive function, behavior, sensory perception, memory retention, cardiovascular health and food intake.

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Parvalbumin: Why You Can't Supplement For Fish

In this post, we will discuss what parvalbumin is, how it plays a role in chronic illnesses, and what you can do to  increase it. 

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How To Remove Uranium From Brain And Body Tissue

In this post we will discuss the downsides of uranium and proven/effective methods for protecting/removing uranium from the body.

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The 10+ Benefits Of Oak Wood (Robuvit and Quercus Species)

Robuvit and Oak Wood extracts from the Quercus species have shown to have very promising results in combating fatigue in human trials.

In the post, we will discuss the benefits of Quercus species and my experience with supplementing Robuvit. 

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The 14+ Benefits of PeaLut / Glialia (Palmitoylethanolamide + Luteolin)

PeaLut is the combination of two powerful components that when combined can abolish inflammation, increase hippocampal growth, and reduce pain.

In this post, we will discuss the benefits of PeaLut and where to buy it.

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The 28+ Benefits Of Embelin And Its Natural Sources

Embelin suppresses cancer, combats inflammation, ameliorates autoimmunity, and destroys many infectious agents.

It also has anti-diabetic, anti-obesity, neuroprotective, and cardioprotective protective effects.

In this post, we will discuss the MANY benefits of embelin, its natural sources, and some synergies of embelin.

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The 7+ Benefits Of Suvorexant (Belsomra): A Dual Orexin Receptor Antagonist

Suvorexant is a dual-orexin receptor antagonist that improves insomnia.

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All About Histamine H3 Receptors (HRH3/HR3): Genetics, Mechanisms, And Antagonists

Is histamine a villain… or really a superhero?

It really depends on which receptor it works on and where it is in the body.

In this post, we will discuss how to use the 3rd histamine receptor to boost cognition, memory, and attention.

We will first discuss how the histamine receptors work.

Then, we will move onto the benefits (and downsides) of blocking Histamine H3 Receptor's (HRH3 or H3R) activity with natural and pharmacological methods.

Lastly, we will discuss the potential benefits of increasing HRH3 with some agonists, HRH3's mechanism of action, and some important HRH3 SNPs.

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HOMER1, HOMER2, and HOMER3: How These Homologs Promote Strong Synaptic Plasticity

In this post, we will discuss Homer proteins (mainly homer1), their implicated diseases with dysregulation, and some novel ways to help with homeostasis.

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The 8+ Benefits Of J147: A Potent Curcumin Derivative (And How To Make T-006)

Unlike the current drugs approved for Alzheimer's Disease, J147 is neither an acetylcholinesterase inhibitor nor a phosphodiesterase inhibitor, yet it enhances cognition with a short-term treatment.

In this post, we will discuss how the curcumin derivative J147 improves memory and I'll explain a very powerful alternative way to get its benefits.

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PON1: Increase Longevity And Detox Pesticides with 99+ Ways To Increase Paraoxonase 1

Paraoxonase 1 (PON1) is an enzyme that plays a role in most diseases.

In this post, we will discuss how you can use PON1 to improve overall health, longevity, and detox mechanisms.  

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Humanin: 7+ Ways To Increase Mitochondria's IGF-1

The term Humanin (HN) was coined by its discoverer, Professor Nishimoto, to denote the potential of this molecule to restore the “humanity” of patients with Alzheimer’s disease. 

Later we have found humanin protects cells from oxidative stress, serum starvation, hypoxia, and other insults as well as also improves cardiovascular disease and Alzheimer's disease. 

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How To Inhibit Lipopolysaccharides (LPS), Lipoglycans, and Endotoxins

Recent data suggests that chronically low levels of circulating LPS may be associated with the development of metabolic diseases such as insulin resistance, type 2 diabetes, atherosclerosis and cardiovascular disease. R

In this post, we will discuss how LPS affects the body and how to reverse endotoxemia.

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Hormesis: What Doesn't Kill You Makes You Stronger

When you optimize your body and fix all deficiencies, where is there to go next in enhancing your body?

Well there is hormesis, which is a very powerful tool for enhancing all aspects of your life.

Hormesis, if done properly can strengthen metabolism, longevity, and wellbeing as well as protect you from chronic illness in general.

In this post we will discus what hormesis is, how to do it, and what to watch out for so you can do it properly.

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The Role of DARPP-32 In Addiction, Schizophrenia & Parkinson's Disease

In this post, we will discuss how protein phosphatase 1 regulatory subunit 1B (PPP1R1B), also known as dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32) plays a large role addiction, Parkinson's Disease, schizophrenia, cognition, and cancer. 

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256+ Ways To Increase Dopamine Naturally (Supplements And Genetics)

Dopamine is extremely important for everyday function and plays a much larger role in the body than just bonding, motivation, cognition, emotion, well-being, and movement.

Unfortunately, our environment today is very good at manipulating and hijacking our dopamine system.

In this post we will discuss, how/why dopamine is produced, how chronic inflammation affects dopamine, what are some quick fixes for dopamine, and what are some long lasting dopamine builders, as well how to avoid losing dopamine. 

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Mycotoxins and Dopamine

Update to my life: I have damage to my caudate and putamen, two parts of the striatum that are responsible for dopamine neurotransmission and synthesis.

My caudate is small (atrophy) and my putamen is enlarged (inflamed).

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