All About Histamine H3 Receptors (HRH3/HR3): Genetics, Mechanisms, And Antagonists

Is histamine a villain… or really a superhero?

It really depends on which receptor it works on and where it is in the body.

In this post, we will discuss how to use the 3rd histamine receptor to boost cognition, memory, and attention.

We will first discuss how the histamine receptors work.

Then, we will move onto the benefits (and downsides) of blocking Histamine H3 Receptor's (HRH3 or H3R) activity with natural and pharmacological methods.

Lastly, we will discuss the potential benefits of increasing HRH3 with some agonists, HRH3's mechanism of action, and some important HRH3 SNPs.

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How To Run While Sitting Down: Exercise Mimetics

Exercise Mimetics are novel ways of getting the benefits of exercising, without having to exercise.

In this post, we will discuss the benefits and mechanisms of exercise and some possible ways to replace exercise. 

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Humanin: 7+ Ways To Increase Mitochondria's IGF-1

The term Humanin (HN) was coined by its discoverer, Professor Nishimoto, to denote the potential of this molecule to restore the “humanity” of patients with Alzheimer’s disease. 

Later we have found humanin protects cells from oxidative stress, serum starvation, hypoxia, and other insults as well as also improves cardiovascular disease and Alzheimer's disease. 

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How To Have Your Cake And Eat It Too: Calorie Restriction And Fasting Mimetics

Calorie Restriction Mimetics (CRMs) are compounds that can induce the same mechanisms as eating less, without having to actually eat less. 

In this post, we will discuss how to have your cake (food) and eat it too. 

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256+ Ways To Increase Dopamine Naturally (Supplements And Genetics)

Dopamine is extremely important for everyday function and plays a much larger role in the body than just bonding, motivation, cognition, emotion, well-being, and movement.

Unfortunately, our environment today is very good at manipulating and hijacking our dopamine system.

In this post we will discuss, how/why dopamine is produced, how chronic inflammation affects dopamine, what are some quick fixes for dopamine, and what are some long lasting dopamine builders, as well how to avoid losing dopamine. 

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The 13+ Benefits Of BPC-157 (Body Protective Compound) and sources

Body Protective Compound 157 (BPC-157) is a peptide that has been recently studied to produce systemic effects on both the brain and the gut, and repair those systems.

In this post, we will discuss the benefits of BPC-157, its mechanism of action, experiences, and where to get it from a quality source.

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How Cadmium Damages Mitochondria And What To Do About It

In western society, cadmium (Cd) is found in our everyday environment.

It causes toxic effects to the whole body, including the cells and mitochondria.

In this post, we will discuss how cadmium affects the body and what you can do to protect yourself.

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Klotho: Become Smarter And Live Longer With 50+ Ways To Increase Klotho

Klotho may be one of our humans' natural adaptogens by its ability to help regulate cellular stress.

In this post, we will discuss its role in longevity, muscle strength, cancer, cognition, and neurotransmitter balance.

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The 17+ Benefits Of Huang-Bai

Huang-Bai has been used in Traditional Chinese Medicine (TCM) for the treatment of depression, meningitis, bacillary dysentery, pneumonia, tuberculosis, and liver cirrhosis. R

In this post, we'll discuss it's benefits, mechanism of action, and properties of different blends of this herb.

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