The 7+ Benefits of Rubiscolins (Opioid Peptide From Rubisco)

Rubiscolins are naturally occurring opioid peptides that come from Spinach.

In this post, we will discuss the benefits of Rubsicolin (-5 and -6) and their mechanism of action.

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32+ Zeitgebers (Biological Cues) And How To Enhance Your Circadian Rhythm

Right now as I write this, I am watching the morning sun, sitting on a bench in Dolores Park with my shirt off an laptop out - in 50ºF weather!

Last night I had no sleep as I just traveled from FL to CA and helping my brother pack until 4am… and I woke up around 5am (8am my normal time… thanks jetlag).

That’s why I believe today’s topic of discussion should be circadian rhythm cues, also called Zeitgebers.

Zeitgebers (the German word for “time givers”) are signals that help synchronize the body's circadian clock with the environment.

In this post, we will discuss the most common zeitgebers, how they affect our circadian rhythm, and how we can use them to enhance our sleep, stress, weight, social life, and more.

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The 35+ Benefits Of French Maritime Pine Bark (Pycnogenol, Flavangenol And Oligopin)

n this post, we will discuss the benefits of French Maritime Pine Bark and Pycnogenol as well as their mechanisms of action.

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Why Do I Get Body Buzzing And/Or Internal Tremors?

Do you get the odd sensation of body buzzing like your body is moving when you are completely still?

The feeling could be when laying down at the end of the day, but it feels like something is either buzzing next to you or inside of you.

These are what I call Internal Tremors or Body Buzzing.

This is not primarily anxiety based, although the unknown cause of this odd phenomenon can trigger anxious feelings. 

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The 16+ Benefits Of Catuaba (Trichilia Catigua And Other Catuabas)

Catuaba is a powerful plant that can improve depression, anxiety, fatigue, and more.

In this post, we will discuss the different forms of Catuaba (true vs non-true catuabas), the benefits of catuaba, and dosage of catuaba.

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The 27+ Benefits Of Matrine (with Natural Sources And Mechanisms)

Matrine is a very powerful alkaloid that has many neuropharmalogical benefits.

In this post, we will discuss matrine's benefits, natural sources for it, and some of matrine's 195+ mechanisms.

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The 8+ Benefits Of Sophoraflavanone G (with Mechanisms and Natural Sources)

Sophoraflavanone G (SG) is a flavonoid and phytoncide with powerful effects on quenching inflammation and fighting microbes.

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The 28+ Benefits Of Embelin And Its Natural Sources

Embelin suppresses cancer, combats inflammation, ameliorates autoimmunity, and destroys many infectious agents.

It also has anti-diabetic, anti-obesity, neuroprotective, and cardioprotective protective effects.

In this post, we will discuss the MANY benefits of embelin, its natural sources, and some synergies of embelin.

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The 12+ Benefits of Wrightia Tinctoria (Indrajauis, Shwetha Kutaja, Pala Indigo)

Wrightia tinctoria is medicinal plant that can improve skin quality and prevent metabolic disease.

In this post, we will discuss its benefits, how to use it, and it's medicinal mechanism.

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All About Histamine H3 Receptors (HRH3/HR3): Genetics, Mechanisms, And Antagonists

Is histamine a villain… or really a superhero?

It really depends on which receptor it works on and where it is in the body.

In this post, we will discuss how to use the 3rd histamine receptor to boost cognition, memory, and attention.

We will first discuss how the histamine receptors work.

Then, we will move onto the benefits (and downsides) of blocking Histamine H3 Receptor's (HRH3 or H3R) activity with natural and pharmacological methods.

Lastly, we will discuss the potential benefits of increasing HRH3 with some agonists, HRH3's mechanism of action, and some important HRH3 SNPs.

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The 14+ Benefits Of Kutaj & Kwatha (Holarrhena antidysenterica)

In this post, we will discuss the Ayurvedic herb, Kutaja, its many benefits, mechanism, and what to watch out for.

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The 8+ Benefits Of J147: A Potent Curcumin Derivative (And How To Make T-006)

Unlike the current drugs approved for Alzheimer's Disease, J147 is neither an acetylcholinesterase inhibitor nor a phosphodiesterase inhibitor, yet it enhances cognition with a short-term treatment.

In this post, we will discuss how the curcumin derivative J147 improves memory and I'll explain a very powerful alternative way to get its benefits.

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The 4+ Benefits Of ALAnerv (With An Improved Alternative)

ALAnerv is a nutritional supplement that has shown have promising effects in improving Stroke, Diabetes, Spinal Cord Injuries, and Painful Bladder Syndrome.

In this post, we will break down what is in ALAnerv, provide an alternative to it, and my experience with the alternative form.

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How To Run While Sitting Down: Exercise Mimetics

Exercise Mimetics are novel ways of getting the benefits of exercising, without having to exercise.

In this post, we will discuss the benefits and mechanisms of exercise and some possible ways to replace exercise. 

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DJ-1/PARK7: How To Revive NRF2 (with 27+ Ways To Increase Protein Deglycase DJ-1)

Protein deglycase DJ-1 (DJ-1), also known as Parkinson disease protein 7 (PARK7) is a master regulator of redox status.

In this post, we will discuss how DJ-1 increases dopamine, enhances mitochondria, and combats most oxidative-stress related diseases. 

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The 27+ Benefits Of Burdock (Arctium lappa)

Burdock root has been used for centuries (over 3000 years) in China and in traditional Chinese medicine (TCM) for "purifying the blood", but in this post we will discuss the actual ways burdock works on improving the body.

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256+ Ways To Increase Dopamine Naturally (Supplements And Genetics)

Dopamine is extremely important for everyday function and plays a much larger role in the body than just bonding, motivation, cognition, emotion, well-being, and movement.

Unfortunately, our environment today is very good at manipulating and hijacking our dopamine system.

In this post we will discuss, how/why dopamine is produced, how chronic inflammation affects dopamine, what are some quick fixes for dopamine, and what are some long lasting dopamine builders, as well how to avoid losing dopamine. 

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Neuropeptides and Autophagy

Two key players in healthy aging are proper neuropeptide signaling and healthy induction of autophagy. R

In this post, we will discuss how neuropeptides either induce or inhibit autophagy.

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The 13+ Benefits Of Chitosan And Chitooligosaccharides

In this post, we will discuss the benefits of chitosan and chitosan derivatives.

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The 10+ Benefits Of Java Tea (Orthosiphon stamineus)

In this post, we will discuss the benefits of Java (Orthosiphon stamineusis), my experience with Java, and where to get the best form. 

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