The 27+ Benefits Of Matrine (with Natural Sources And Mechanisms)

Matrine is a very powerful alkaloid that has many neuropharmalogical benefits.

In this post, we will discuss matrine's benefits, natural sources for it, and some of matrine's 195+ mechanisms.

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DJ-1/PARK7: How To Revive NRF2 (with 27+ Ways To Increase Protein Deglycase DJ-1)

Protein deglycase DJ-1 (DJ-1), also known as Parkinson disease protein 7 (PARK7) is a master regulator of redox status.

In this post, we will discuss how DJ-1 increases dopamine, enhances mitochondria, and combats most oxidative-stress related diseases. 

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Root Causes Of Postural Orthostatic Tachycardia Syndrome (POTS) And Ways To Reverse It

In this post, we will discuss root causes of Postural orthostatic tachycardia syndrome (POTS) and cutting-edge ways to reverse it and the symptoms.

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How To Have Your Cake And Eat It Too: Calorie Restriction And Fasting Mimetics

Calorie Restriction Mimetics (CRMs) are compounds that can induce the same mechanisms as eating less, without having to actually eat less. 

In this post, we will discuss how to have your cake (food) and eat it too. 

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Vasohibin-2 (VASH2): A Key Player In Cancer And Chemoresistance

In this post, we will dicuss how vasohibin-2 (VASH2) plays a role cancer progression and chemoresistance.

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How To Stop Protein Misfolding (Proteopathy)

I tried folding protein once, but all I got was a ham and cheese sandwich.

In this post we're discussing proteopathy, how proteins can cause chronic disease, and some strategies to prevent it all. 

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MANF: What Is It And How To Increase Mesencephalic Astrocyte-Derived Neurotrophic Factor

Mesencephalic astrocyte-derived neurotrophic factor (MANF; also known as ARMET or arginine-rich mutated in early stages of tumor) belongs to the fourth family of neurotrophic factors. 

It plays a huge role in repairing neurons and cells after oxidative stress, and has promising uses for the future in neurodegenerative diseases (such as  Parkinson's Disease).

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Why NRF2 Activation Can Make You More Sick

Recent cancer research has helped us understand how the body detoxes.

By studying upregulated genes in tumorous cells, we were able to find the Nuclear Erythroid 2–Related Factor 2 (NRF2) pathway.

NRF2 is a major transcription factor in detoxing the body and keeping it healthy.

In this post, we will discuss the benefits/downsides of NRF2 activation, as well as why NRF2 may be hurting you more than helping you (and what you can do about it).

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Klotho: Become Smarter And Live Longer With 50+ Ways To Increase Klotho

Klotho may be one of our humans' natural adaptogens by its ability to help regulate cellular stress.

In this post, we will discuss its role in longevity, muscle strength, cancer, cognition, and neurotransmitter balance.

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The 7+ Benefits of Losartan

Typically, losartan is used in treating hypertesion (high blood pressure), but it has many more off-label uses, like improving muscle growth.

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The 12+ Benefits of Metformin

Beyond Diabetes: Fight Cancer, Aging, Dysbiosis

Metformin is a standard anti-diabetic drug, taken by millions since 1957. It is currently being prescribed to over 150 million individuals worldwide.

It is one of the few miracle drugs that has ever been created. 

Many of the benefits metformin seems to have is through increasing production of butyrate and HDAC inhibition, in butyrate deprived diabetes patients. 

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