The 35+ Benefits Of French Maritime Pine Bark (Pycnogenol, Flavangenol And Oligopin)

n this post, we will discuss the benefits of French Maritime Pine Bark and Pycnogenol as well as their mechanisms of action.

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The 29+ Benefits Of Sophora flavescens (Ku Shen)

Ku shen (sophora flavescens) is a root with powerful effects on cancer, metabolic diseases, neurological disorders and more.

In this post, we will discuss the benefits of ku shen, its caveats, and where to buy ku shen.

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Parvalbumin: Why You Can't Supplement For Fish

In this post, we will discuss what parvalbumin is, how it plays a role in chronic illnesses, and what you can do to  increase it. 

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The 22+ Benefits Of Oxymatrine (With Natural Sources, Synergies, And Mechanisms)

Oxymatrine has shown to have anti-arrhythmic, immune regulatory, and anti-tumor properties and is used in China for treatment of viral hepatitis, cancer, cardiac diseases (such as viral myocarditis), and skin diseases (such as psoriasis and eczema). R

In this post, we will discuss the many benefits of oxymatrine, its natural sources, and its mechanisms.

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Discoidin Domain Receptors (DDR1 and DDR2): Activators And Inhibitors

DDR1 and DDR2 are tyrosine kinase receptors in the extracellular matrix that mediate mediate cell aggregation.

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The 28+ Benefits Of Embelin And Its Natural Sources

Embelin suppresses cancer, combats inflammation, ameliorates autoimmunity, and destroys many infectious agents.

It also has anti-diabetic, anti-obesity, neuroprotective, and cardioprotective protective effects.

In this post, we will discuss the MANY benefits of embelin, its natural sources, and some synergies of embelin.

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All About Histamine H3 Receptors (HRH3/HR3): Genetics, Mechanisms, And Antagonists

Is histamine a villain… or really a superhero?

It really depends on which receptor it works on and where it is in the body.

In this post, we will discuss how to use the 3rd histamine receptor to boost cognition, memory, and attention.

We will first discuss how the histamine receptors work.

Then, we will move onto the benefits (and downsides) of blocking Histamine H3 Receptor's (HRH3 or H3R) activity with natural and pharmacological methods.

Lastly, we will discuss the potential benefits of increasing HRH3 with some agonists, HRH3's mechanism of action, and some important HRH3 SNPs.

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Thomas E. Levy MD JD - Vitamin C, Calcium, Iron and Root Canals

Dr. Thomas E Levy and I discuss common misconceptions about disease, specifically: vitamin C, calcium, iron and root canals.

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Dr. Denis Wilson - Wilson Temperature Syndrome and Regulating Thyroid Function Without Blood Tests

Dr. Denis Wilson and I discuss how to monitor and regulate thyroid function without the need for blood tests.

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Dr. Nathan Bryan - All About Nitric Oxide In The Body and Chronic Disease

Dr. Nathan Bryan and I discuss a common underlying problem in most chronic illness - dysregulation of nitric oxide

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HOMER1, HOMER2, and HOMER3: How These Homologs Promote Strong Synaptic Plasticity

In this post, we will discuss Homer proteins (mainly homer1), their implicated diseases with dysregulation, and some novel ways to help with homeostasis.

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PON1: Increase Longevity And Detox Pesticides with 99+ Ways To Increase Paraoxonase 1

Paraoxonase 1 (PON1) is an enzyme that plays a role in most diseases.

In this post, we will discuss how you can use PON1 to improve overall health, longevity, and detox mechanisms.  

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Humanin: 7+ Ways To Increase Mitochondria's IGF-1

The term Humanin (HN) was coined by its discoverer, Professor Nishimoto, to denote the potential of this molecule to restore the “humanity” of patients with Alzheimer’s disease. 

Later we have found humanin protects cells from oxidative stress, serum starvation, hypoxia, and other insults as well as also improves cardiovascular disease and Alzheimer's disease. 

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DJ-1/PARK7: How To Revive NRF2 (with 27+ Ways To Increase Protein Deglycase DJ-1)

Protein deglycase DJ-1 (DJ-1), also known as Parkinson disease protein 7 (PARK7) is a master regulator of redox status.

In this post, we will discuss how DJ-1 increases dopamine, enhances mitochondria, and combats most oxidative-stress related diseases. 

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Root Causes Of Postural Orthostatic Tachycardia Syndrome (POTS) And Ways To Reverse It

In this post, we will discuss root causes of Postural orthostatic tachycardia syndrome (POTS) and cutting-edge ways to reverse it and the symptoms.

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How Jet Fumes And Hypoxia On Planes Affect The Body

Hypoxia (loss of oxygen) is a major stressor on the body.

On average, one can live ~21 days without food, ~2 days without water, but only a few minutes without oxygen. R

Most studies review long term exposure of hypoxia, but in this post we will discuss what happens to the body on a cellular level when exposed to hypoxia in the short term, such as flying or space travel (in a non-hormetic way).

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How To Have Your Cake And Eat It Too: Calorie Restriction And Fasting Mimetics

Calorie Restriction Mimetics (CRMs) are compounds that can induce the same mechanisms as eating less, without having to actually eat less. 

In this post, we will discuss how to have your cake (food) and eat it too. 

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How To Inhibit Lipopolysaccharides (LPS), Lipoglycans, and Endotoxins

Recent data suggests that chronically low levels of circulating LPS may be associated with the development of metabolic diseases such as insulin resistance, type 2 diabetes, atherosclerosis and cardiovascular disease. R

In this post, we will discuss how LPS affects the body and how to reverse endotoxemia.

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Hormesis: What Doesn't Kill You Makes You Stronger

When you optimize your body and fix all deficiencies, where is there to go next in enhancing your body?

Well there is hormesis, which is a very powerful tool for enhancing all aspects of your life.

Hormesis, if done properly can strengthen metabolism, longevity, and wellbeing as well as protect you from chronic illness in general.

In this post we will discus what hormesis is, how to do it, and what to watch out for so you can do it properly.

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The 27+ Benefits Of Burdock (Arctium lappa)

Burdock root has been used for centuries (over 3000 years) in China and in traditional Chinese medicine (TCM) for "purifying the blood", but in this post we will discuss the actual ways burdock works on improving the body.

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