Bring Out Your Dead… I’m Not Dead Yet (8+ Benefits Of Reducing Indy)

Reducing the expression of the gene Indy has shown to improve the health and longevity of humans, flies, mice, and worms.

In this post, we will discuss the benefits of lower Indy levels and how to prevent higher INDY levels.

Read More

The 35+ Benefits Of French Maritime Pine Bark (Pycnogenol, Flavangenol And Oligopin)

n this post, we will discuss the benefits of French Maritime Pine Bark and Pycnogenol as well as their mechanisms of action.

Read More

10+ Reasons Why Alcohol Intolerance Happens And How To Build Alcohol Tolerance (Mechanisms And Genetics)

Are you someone who could handle their alcohol until getting sick, then any sort of alcohol in any amount may make you sick?

This is a common problem with those after their immune system has gone haywire.

In this post, I will breakdown and discuss mechanisms behind the loss of tolerance towards alochol

Read More

The 27+ Benefits Of Ecklonia Cava and Phlorotannins

Ecklonia cava is a powerful brown algae that shows promising potential in many metabolic diseases.

In this post, we will discuss the benefits of Ecklonia cava, where to buy it, and its mechanism of action.

Read More

The 22+ Benefits Of Oxymatrine (With Natural Sources, Synergies, And Mechanisms)

Oxymatrine has shown to have anti-arrhythmic, immune regulatory, and anti-tumor properties and is used in China for treatment of viral hepatitis, cancer, cardiac diseases (such as viral myocarditis), and skin diseases (such as psoriasis and eczema). R

In this post, we will discuss the many benefits of oxymatrine, its natural sources, and its mechanisms.

Read More

PON1: Increase Longevity And Detox Pesticides with 99+ Ways To Increase Paraoxonase 1

Paraoxonase 1 (PON1) is an enzyme that plays a role in most diseases.

In this post, we will discuss how you can use PON1 to improve overall health, longevity, and detox mechanisms.  

Read More

How To Run While Sitting Down: Exercise Mimetics

Exercise Mimetics are novel ways of getting the benefits of exercising, without having to exercise.

In this post, we will discuss the benefits and mechanisms of exercise and some possible ways to replace exercise. 

Read More

Are You ApoE4? 88+ Ways To Increase Apolipoprotein E (ApoE)

ApoE is a master regulator for many genes implicated in cholesterol metabolism (such as Alzheimer's Disease and Atherosclerosis).

In this post, we will discuss the benefits and downsides of ApoE, how to determine if you are ApoE2, E3, or E4, and ways to fix it.

Read More

DJ-1/PARK7: How To Revive NRF2 (with 27+ Ways To Increase Protein Deglycase DJ-1)

Protein deglycase DJ-1 (DJ-1), also known as Parkinson disease protein 7 (PARK7) is a master regulator of redox status.

In this post, we will discuss how DJ-1 increases dopamine, enhances mitochondria, and combats most oxidative-stress related diseases. 

Read More

How To Inhibit Lipopolysaccharides (LPS), Lipoglycans, and Endotoxins

Recent data suggests that chronically low levels of circulating LPS may be associated with the development of metabolic diseases such as insulin resistance, type 2 diabetes, atherosclerosis and cardiovascular disease. R

In this post, we will discuss how LPS affects the body and how to reverse endotoxemia.

Read More

How Cadmium Damages Mitochondria And What To Do About It

In western society, cadmium (Cd) is found in our everyday environment.

It causes toxic effects to the whole body, including the cells and mitochondria.

In this post, we will discuss how cadmium affects the body and what you can do to protect yourself.

Read More

Why NRF2 Activation Can Make You More Sick

Recent cancer research has helped us understand how the body detoxes.

By studying upregulated genes in tumorous cells, we were able to find the Nuclear Erythroid 2–Related Factor 2 (NRF2) pathway.

NRF2 is a major transcription factor in detoxing the body and keeping it healthy.

In this post, we will discuss the benefits/downsides of NRF2 activation, as well as why NRF2 may be hurting you more than helping you (and what you can do about it).

Read More

The 21+ Benefits Of Beta-Caryophyllene (The Common Cannabinoid)

Beta-Caryophyllene Is A Very Common Cannabinoid

β-caryophyllene is a FDA-approved food additive that can activate the endocannabinoid system. 

It is found in many plants, fragerances, preservatives, additives, and flavoring agents.

Read More

The 13+ Benefits Of Chokeberries (Aronia)

The Herb With The Strongest Polyphenol Count
Chokeberries (Aronia) are powerful anti-oxidants and anti-inflammatories as they are very high in polyphenols

Read More

The 18+ Benefits Of Tianma and Gastrodin

Tianma and Its 81+ Major Compounds

Tianma (also called Gastrodia Elata) works on many systems of the body including the brain, liver, heart, eyes, ears, bones, and lungs.

It has many potential benefits in preventing treating common neurological and metabolic disorders such as Alzheimer's, Parkinson's, Huntington's, epilepsy, liver disease, diabetes, neuropathy, and more.

In this post, we are going to be talking about Tianma, its bioactive components, and their benefits.

Read More

The 8+ Benefits Of Deferoxamine

Deferoxamine is a powerful drug that has potential benefits in restoring neuronal health, especially in those with stroke, Alzheimer's Disease, Parkinson's Disease, spinal cord injury and sleep disorders.

In this post I've gone through it's potential benefits and alternatives to this drug. 

Read More

Artificial Sweeteners Alter Signaling In The Brain and Pancreas

Not all artificial sweeteners aka (nonnutritive sweeteners (NNSs) or low-calorie sweeteners (LCS)) are bad. 

Use of artificially sweetened foods (ASF) has increased in the past 50 years in the USA and there are clear parallels with changes in the prevalence of being overweight and the rise of obesity. R

Just because something is deemed as "safe" by the FDA, does not make it safe for humans.

In this post, I will break down the effects of artificial sweeteners on the body and give an alternative list to which ones are "safer" or even beneficial

Read More

Why You Need To Get Out Into The Sun

In common day western society, we are consistently bombarded by artificial light.

Our workspaces are indoors, powered by fluorescent blue lights (which blue has its own negatives).

We only get sun rarely and it's either partial (such as through glass while driving to work) or too much (single sessions of long periods hanging out at the beach).

We also try to supplement for the sun by taking vitamin D hormone supplements, which is not as bioactive for creating the active form vitamin D.

Read More

The 10+ Benefits of Liraglutide

Liraglutide protects the brain, improve weight loss, and protect against many of the problems associated with metabolic syndromes.

A lot of its effects with diabetes, obesity and the brain are based on liraglutide's ability to change the composition of the gut microbiome.

Read More

The 9+ Benefits of Irisin And How To Increase It Naturally

Irisin is an anti-obesity and anti-diabetes hormone that regulates fat tissue and blood sugar.

Irisin is generated by exercise and acts as an insulin-sensitizing hormone.

Irisin is so powerful that even moderately increased levels of circulating irisin potently increases energy expenditure, reduces body weight and improves diet-induced insulin resistance.

Read More