Mast Cells (Part 3): The Mast Cell-Glia Interaction In Chronic Inflammation

In this post we will focus on the mast cell-glia (microglia, astrocyte, oligodendrocyte) interaction with our body and how they contribute to chronic inflammatory diseases such as CIRS and SALI.

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32+ Zeitgebers (Biological Cues) And How To Enhance Your Circadian Rhythm

Right now as I write this, I am watching the morning sun, sitting on a bench in Dolores Park with my shirt off an laptop out - in 50ºF weather!

Last night I had no sleep as I just traveled from FL to CA and helping my brother pack until 4am… and I woke up around 5am (8am my normal time… thanks jetlag).

That’s why I believe today’s topic of discussion should be circadian rhythm cues, also called Zeitgebers.

Zeitgebers (the German word for “time givers”) are signals that help synchronize the body's circadian clock with the environment.

In this post, we will discuss the most common zeitgebers, how they affect our circadian rhythm, and how we can use them to enhance our sleep, stress, weight, social life, and more.

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The 35+ Benefits Of French Maritime Pine Bark (Pycnogenol, Flavangenol And Oligopin)

n this post, we will discuss the benefits of French Maritime Pine Bark and Pycnogenol as well as their mechanisms of action.

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The 29+ Benefits Of Sophora flavescens (Ku Shen)

Ku shen (sophora flavescens) is a root with powerful effects on cancer, metabolic diseases, neurological disorders and more.

In this post, we will discuss the benefits of ku shen, its caveats, and where to buy ku shen.

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Parvalbumin: Why You Can't Supplement For Fish

In this post, we will discuss what parvalbumin is, how it plays a role in chronic illnesses, and what you can do to  increase it. 

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The 16+ Benefits Of Catuaba (Trichilia Catigua And Other Catuabas)

Catuaba is a powerful plant that can improve depression, anxiety, fatigue, and more.

In this post, we will discuss the different forms of Catuaba (true vs non-true catuabas), the benefits of catuaba, and dosage of catuaba.

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Do You Have Systemic And Long-term Inflammation? (SALI)

Do you have CIRS that does not go away with the traditional or manipulated versions of the protocol?

In this post, we will discuss what is SALI and how this may be a better way to look at similar chronic diseases.

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The 22+ Benefits Of Oxymatrine (With Natural Sources, Synergies, And Mechanisms)

Oxymatrine has shown to have anti-arrhythmic, immune regulatory, and anti-tumor properties and is used in China for treatment of viral hepatitis, cancer, cardiac diseases (such as viral myocarditis), and skin diseases (such as psoriasis and eczema). R

In this post, we will discuss the many benefits of oxymatrine, its natural sources, and its mechanisms.

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The 27+ Benefits Of Matrine (with Natural Sources And Mechanisms)

Matrine is a very powerful alkaloid that has many neuropharmalogical benefits.

In this post, we will discuss matrine's benefits, natural sources for it, and some of matrine's 195+ mechanisms.

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HOMER1, HOMER2, and HOMER3: How These Homologs Promote Strong Synaptic Plasticity

In this post, we will discuss Homer proteins (mainly homer1), their implicated diseases with dysregulation, and some novel ways to help with homeostasis.

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Are You ApoE4? 88+ Ways To Increase Apolipoprotein E (ApoE)

ApoE is a master regulator for many genes implicated in cholesterol metabolism (such as Alzheimer's Disease and Atherosclerosis).

In this post, we will discuss the benefits and downsides of ApoE, how to determine if you are ApoE2, E3, or E4, and ways to fix it.

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The 27+ Benefits Of Burdock (Arctium lappa)

Burdock root has been used for centuries (over 3000 years) in China and in traditional Chinese medicine (TCM) for "purifying the blood", but in this post we will discuss the actual ways burdock works on improving the body.

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256+ Ways To Increase Dopamine Naturally (Supplements And Genetics)

Dopamine is extremely important for everyday function and plays a much larger role in the body than just bonding, motivation, cognition, emotion, well-being, and movement.

Unfortunately, our environment today is very good at manipulating and hijacking our dopamine system.

In this post we will discuss, how/why dopamine is produced, how chronic inflammation affects dopamine, what are some quick fixes for dopamine, and what are some long lasting dopamine builders, as well how to avoid losing dopamine. 

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The 13+ Benefits Of Chitosan And Chitooligosaccharides

In this post, we will discuss the benefits of chitosan and chitosan derivatives.

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The 18+ Benefits of Hops (Humulus lupulus)

Have you ever wondered what gave beer its bitter, "hoppy" taste and aroma?

Well the answer is hops. 😋

In this post, we'll be discussing the benefits of hops, how it works on the body, and some non-alcoholic benefits of beer

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May The Forest Bathe With You (Biohacking Shinrin-Yoku)

Have you ever wondered why you feel so good on hikes?

I know when I go out, it feels almost like there is some magic to being outdoors - I get invigorated, happy, and just feel alive. 

Well, there are biological effects to being outside.

This practice of going outside has been thoroughly investigated and given the name “Shinrin-Yoku” in Japan, aka “Forest Bathing”.

In this post, we’re going to discuss Forest Bathing’s scientifically proven benefits, what really is going on from being in nature, and what you can do to biohack its effects (without having to go outside). 😉

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The 11+ Benefits Of Maqui (Aristotelia Chilensis)

Maqui (also known as Chilean wineberry, or Chilean blackberry) is a plant native to Chile and Argentina. 

Its berries and leaves have profound bioactive health benefits, which we will discuss in this post.

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MANF: What Is It And How To Increase Mesencephalic Astrocyte-Derived Neurotrophic Factor

Mesencephalic astrocyte-derived neurotrophic factor (MANF; also known as ARMET or arginine-rich mutated in early stages of tumor) belongs to the fourth family of neurotrophic factors. 

It plays a huge role in repairing neurons and cells after oxidative stress, and has promising uses for the future in neurodegenerative diseases (such as  Parkinson's Disease).

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Why NRF2 Activation Can Make You More Sick

Recent cancer research has helped us understand how the body detoxes.

By studying upregulated genes in tumorous cells, we were able to find the Nuclear Erythroid 2–Related Factor 2 (NRF2) pathway.

NRF2 is a major transcription factor in detoxing the body and keeping it healthy.

In this post, we will discuss the benefits/downsides of NRF2 activation, as well as why NRF2 may be hurting you more than helping you (and what you can do about it).

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The 14+ Benefits Of Amentoflavone

Amentoflavone Is Cool (AF) :D
Amentoflavone (AF) is a naturally occurring biflavonoid found in many (over 120) natural plants, such as Gingko Biloba and St. John's Wort.

 

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