The 29+ Benefits Of Sophora flavescens (Ku Shen)

Ku shen (sophora flavescens) is a root with powerful effects on cancer, metabolic diseases, neurological disorders and more.

In this post, we will discuss the benefits of ku shen, its caveats, and where to buy ku shen.

Read more

The 27+ Benefits Of Ecklonia Cava and Phlorotannins

Ecklonia cava is a powerful brown algae that shows promising potential in many metabolic diseases.

In this post, we will discuss the benefits of Ecklonia cava, where to buy it, and its mechanism of action.

Read more

How Essential Oils And Fragrances Cause Sensitization And Fragrance Intolerance

It is paramount to know how to use essential oils correctly.

Improper usage can cause lasting (possibly permanent) side effects and immune sensitization.

In this post, we will discuss how to use essential oils properly and potential sources for hidden essential oils.

Read more

The 22+ Benefits Of Oxymatrine (With Natural Sources, Synergies, And Mechanisms)

Oxymatrine has shown to have anti-arrhythmic, immune regulatory, and anti-tumor properties and is used in China for treatment of viral hepatitis, cancer, cardiac diseases (such as viral myocarditis), and skin diseases (such as psoriasis and eczema). R

In this post, we will discuss the many benefits of oxymatrine, its natural sources, and its mechanisms.

Read more

The 27+ Benefits Of Matrine (with Natural Sources And Mechanisms)

Matrine is a very powerful alkaloid that has many neuropharmalogical benefits.

In this post, we will discuss matrine's benefits, natural sources for it, and some of matrine's 195+ mechanisms.

Read more

How GPR84 Senses And Potentiates Inflammation

GPR84 is an inflammation sensor that plays a role in endotoxemia, brain injuries, and obesity.

In this post, we will discuss how to regulate GPR84's function. 

Read more

All About Histamine H3 Receptors (HRH3/HR3): Genetics, Mechanisms, And Antagonists

Is histamine a villain… or really a superhero?

It really depends on which receptor it works on and where it is in the body.

In this post, we will discuss how to use the 3rd histamine receptor to boost cognition, memory, and attention.

We will first discuss how the histamine receptors work.

Then, we will move onto the benefits (and downsides) of blocking Histamine H3 Receptor's (HRH3 or H3R) activity with natural and pharmacological methods.

Lastly, we will discuss the potential benefits of increasing HRH3 with some agonists, HRH3's mechanism of action, and some important HRH3 SNPs.

Read more

HOMER1, HOMER2, and HOMER3: How These Homologs Promote Strong Synaptic Plasticity

In this post, we will discuss Homer proteins (mainly homer1), their implicated diseases with dysregulation, and some novel ways to help with homeostasis.

Read more

The 8+ Benefits Of J147: A Potent Curcumin Derivative (And How To Make T-006)

Unlike the current drugs approved for Alzheimer's Disease, J147 is neither an acetylcholinesterase inhibitor nor a phosphodiesterase inhibitor, yet it enhances cognition with a short-term treatment.

In this post, we will discuss how the curcumin derivative J147 improves memory and I'll explain a very powerful alternative way to get its benefits.

Read more

How Jet Fumes And Hypoxia On Planes Affect The Body

Hypoxia (loss of oxygen) is a major stressor on the body.

On average, one can live ~21 days without food, ~2 days without water, but only a few minutes without oxygen. R

Most studies review long term exposure of hypoxia, but in this post we will discuss what happens to the body on a cellular level when exposed to hypoxia in the short term, such as flying or space travel (in a non-hormetic way).

Read more

256+ Ways To Increase Dopamine Naturally (Supplements And Genetics)

Dopamine is extremely important for everyday function and plays a much larger role in the body than just bonding, motivation, cognition, emotion, well-being, and movement.

Unfortunately, our environment today is very good at manipulating and hijacking our dopamine system.

In this post we will discuss, how/why dopamine is produced, how chronic inflammation affects dopamine, what are some quick fixes for dopamine, and what are some long lasting dopamine builders, as well how to avoid losing dopamine. 

Read more

The 13+ Benefits Of Chitosan And Chitooligosaccharides

In this post, we will discuss the benefits of chitosan and chitosan derivatives.

Read more

Why NRF2 Activation Can Make You More Sick

Recent cancer research has helped us understand how the body detoxes.

By studying upregulated genes in tumorous cells, we were able to find the Nuclear Erythroid 2–Related Factor 2 (NRF2) pathway.

NRF2 is a major transcription factor in detoxing the body and keeping it healthy.

In this post, we will discuss the benefits/downsides of NRF2 activation, as well as why NRF2 may be hurting you more than helping you (and what you can do about it).

Read more

The 4+ Benefits Of NSI-189 (With Mechanisms)

NSI-189 is a new anti-depressant and cognitive booster.

Unlike other antidepressants such as SSRIs or MAOIs, NSI-189 appears to work on other independent mechanisms.

Read more

The 21+ Benefits Of Beta-Caryophyllene (The Common Cannabinoid)

Beta-Caryophyllene Is A Very Common Cannabinoid

β-caryophyllene is a FDA-approved food additive that can activate the endocannabinoid system. 

It is found in many plants, fragerances, preservatives, additives, and flavoring agents.

Read more

The 15+ Benefits Of Copaiba and Copaifera

Copaiba - A Legal Cannabinoid Alternative - Copaiba oil has been used for more than 390 years with benefits towards bronchitis, skin diseases, ulcers, and syphilis. 

Read more

Balancing Excitatory Amino Acid Transporter Activity

Controlling Excitatory Amino Acid Transporters (EAATs) activity is a novel way to reduce excitotoxicity (neuronal damage due to overactivity) in the brain

Read more

The 18+ Benefits Of Tianma and Gastrodin

Tianma and Its 81+ Major Compounds

Tianma (also called Gastrodia Elata) works on many systems of the body including the brain, liver, heart, eyes, ears, bones, and lungs.

It has many potential benefits in preventing treating common neurological and metabolic disorders such as Alzheimer's, Parkinson's, Huntington's, epilepsy, liver disease, diabetes, neuropathy, and more.

In this post, we are going to be talking about Tianma, its bioactive components, and their benefits.

Read more

The 8+ Benefits Of Deferoxamine

Deferoxamine is a powerful drug that has potential benefits in restoring neuronal health, especially in those with stroke, Alzheimer's Disease, Parkinson's Disease, spinal cord injury and sleep disorders.

In this post I've gone through it's potential benefits and alternatives to this drug. 

Read more

The 15+ Benefits of Ziziphus Jujuba (Jujube or Chinese Dates)

Ziziphus jujuba (jujube or Chinese dates), a plant in the family Rhamnaceae, is used in several Asian countries as a food and traditional medicine for over 3000 years. 

The different parts of the Jujube plant (seeds, fruit, leaves, roots, etc) have different functions on the body. 

Read more