Mast Cells (Part 3): The Mast Cell-Glia Interaction In Chronic Inflammation

In this post we will focus on the mast cell-glia (microglia, astrocyte, oligodendrocyte) interaction with our body and how they contribute to chronic inflammatory diseases such as CIRS and SALI.

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32+ Zeitgebers (Biological Cues) And How To Enhance Your Circadian Rhythm

Right now as I write this, I am watching the morning sun, sitting on a bench in Dolores Park with my shirt off an laptop out - in 50ºF weather!

Last night I had no sleep as I just traveled from FL to CA and helping my brother pack until 4am… and I woke up around 5am (8am my normal time… thanks jetlag).

That’s why I believe today’s topic of discussion should be circadian rhythm cues, also called Zeitgebers.

Zeitgebers (the German word for “time givers”) are signals that help synchronize the body's circadian clock with the environment.

In this post, we will discuss the most common zeitgebers, how they affect our circadian rhythm, and how we can use them to enhance our sleep, stress, weight, social life, and more.

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The 35+ Benefits Of French Maritime Pine Bark (Pycnogenol, Flavangenol And Oligopin)

n this post, we will discuss the benefits of French Maritime Pine Bark and Pycnogenol as well as their mechanisms of action.

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Why Do I Get Body Buzzing And/Or Internal Tremors?

Do you get the odd sensation of body buzzing like your body is moving when you are completely still?

The feeling could be when laying down at the end of the day, but it feels like something is either buzzing next to you or inside of you.

These are what I call Internal Tremors or Body Buzzing.

This is not primarily anxiety based, although the unknown cause of this odd phenomenon can trigger anxious feelings. 

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The 16+ Benefits Of Catuaba (Trichilia Catigua And Other Catuabas)

Catuaba is a powerful plant that can improve depression, anxiety, fatigue, and more.

In this post, we will discuss the different forms of Catuaba (true vs non-true catuabas), the benefits of catuaba, and dosage of catuaba.

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The 28+ Benefits Of Embelin And Its Natural Sources

Embelin suppresses cancer, combats inflammation, ameliorates autoimmunity, and destroys many infectious agents.

It also has anti-diabetic, anti-obesity, neuroprotective, and cardioprotective protective effects.

In this post, we will discuss the MANY benefits of embelin, its natural sources, and some synergies of embelin.

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Dr. Nathan Bryan - All About Nitric Oxide In The Body and Chronic Disease

Dr. Nathan Bryan and I discuss a common underlying problem in most chronic illness - dysregulation of nitric oxide

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PON1: Increase Longevity And Detox Pesticides with 99+ Ways To Increase Paraoxonase 1

Paraoxonase 1 (PON1) is an enzyme that plays a role in most diseases.

In this post, we will discuss how you can use PON1 to improve overall health, longevity, and detox mechanisms.  

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Are You ApoE4? 88+ Ways To Increase Apolipoprotein E (ApoE)

ApoE is a master regulator for many genes implicated in cholesterol metabolism (such as Alzheimer's Disease and Atherosclerosis).

In this post, we will discuss the benefits and downsides of ApoE, how to determine if you are ApoE2, E3, or E4, and ways to fix it.

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Humanin: 7+ Ways To Increase Mitochondria's IGF-1

The term Humanin (HN) was coined by its discoverer, Professor Nishimoto, to denote the potential of this molecule to restore the “humanity” of patients with Alzheimer’s disease. 

Later we have found humanin protects cells from oxidative stress, serum starvation, hypoxia, and other insults as well as also improves cardiovascular disease and Alzheimer's disease. 

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DJ-1/PARK7: How To Revive NRF2 (with 27+ Ways To Increase Protein Deglycase DJ-1)

Protein deglycase DJ-1 (DJ-1), also known as Parkinson disease protein 7 (PARK7) is a master regulator of redox status.

In this post, we will discuss how DJ-1 increases dopamine, enhances mitochondria, and combats most oxidative-stress related diseases. 

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How To Remove Gadolinium From Brain And Body Tissue

I have visited ERs and hospitals during my adventure to regain my health and have had my fair share of scans.

If you've ever had a MRI with contrast before, then there's likelihood that you have some levels of the lanthanide element gadolinium stored in your body and/or brain. 

In this post, we will discuss the epigenetic effects of gadolinium and some experimental ways to remove it from the body.

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Root Causes Of Postural Orthostatic Tachycardia Syndrome (POTS) And Ways To Reverse It

In this post, we will discuss root causes of Postural orthostatic tachycardia syndrome (POTS) and cutting-edge ways to reverse it and the symptoms.

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How Jet Fumes And Hypoxia On Planes Affect The Body

Hypoxia (loss of oxygen) is a major stressor on the body.

On average, one can live ~21 days without food, ~2 days without water, but only a few minutes without oxygen. R

Most studies review long term exposure of hypoxia, but in this post we will discuss what happens to the body on a cellular level when exposed to hypoxia in the short term, such as flying or space travel (in a non-hormetic way).

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The 17+ Benefits Of Human Immunoglobulin Therapy

Immunoglobulin therapy has many benefits in treating post-infectious diseases and autoimmunity, but careful consideration but be taken into account before therapy.

In this post, we will discuss the benefits of immunoglobulin therapy, its downsides, and the approved types of immunoglobulin therapies, along with its mechanism of action. 

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115+ Ways To Increase Tyrosine Hydroxylase (And What Decreases It)

Tyrosine hydroxylase is a necessary enzyme to create neurotransmitters and protect the body against oxidative stress.

In this post, we will discuss its benefits, downsides, and ways to increase its activity. 

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The 13+ Benefits Of BPC-157 (Body Protective Compound) and sources

Body Protective Compound 157 (BPC-157) is a peptide that has been recently studied to produce systemic effects on both the brain and the gut, and repair those systems.

In this post, we will discuss the benefits of BPC-157, its mechanism of action, experiences, and where to get it from a quality source.

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Inorganic Vs Organic Mercury (And What To Do About It)

Although it may have had an important role in scientific history, mercury has been found over the years to cause significant damage to the brain and body. 

In this post, we will discuss the different types of mercury, how they affect the body, and what you can do to effectively remove them.

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The 10+ Benefits Of Java Tea (Orthosiphon stamineus)

In this post, we will discuss the benefits of Java (Orthosiphon stamineusis), my experience with Java, and where to get the best form. 

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Why NRF2 Activation Can Make You More Sick

Recent cancer research has helped us understand how the body detoxes.

By studying upregulated genes in tumorous cells, we were able to find the Nuclear Erythroid 2–Related Factor 2 (NRF2) pathway.

NRF2 is a major transcription factor in detoxing the body and keeping it healthy.

In this post, we will discuss the benefits/downsides of NRF2 activation, as well as why NRF2 may be hurting you more than helping you (and what you can do about it).

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