32+ Zeitgebers (Biological Cues) And How To Enhance Your Circadian Rhythm

Right now as I write this, I am watching the morning sun, sitting on a bench in Dolores Park with my shirt off an laptop out - in 50ºF weather!

Last night I had no sleep as I just traveled from FL to CA and helping my brother pack until 4am… and I woke up around 5am (8am my normal time… thanks jetlag).

That’s why I believe today’s topic of discussion should be circadian rhythm cues, also called Zeitgebers.

Zeitgebers (the German word for “time givers”) are signals that help synchronize the body's circadian clock with the environment.

In this post, we will discuss the most common zeitgebers, how they affect our circadian rhythm, and how we can use them to enhance our sleep, stress, weight, social life, and more.

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All About Phoenixin: Pros And Cons Of Phoenixin And GPR173

Phoenixin is a peptide that regulates reproductive function, behavior, sensory perception, memory retention, cardiovascular health and food intake.

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Do You Have Systemic And Long-term Inflammation? (SALI)

Do you have CIRS that does not go away with the traditional or manipulated versions of the protocol?

In this post, we will discuss what is SALI and how this may be a better way to look at similar chronic diseases.

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The 22+ Benefits Of Oxymatrine (With Natural Sources, Synergies, And Mechanisms)

Oxymatrine has shown to have anti-arrhythmic, immune regulatory, and anti-tumor properties and is used in China for treatment of viral hepatitis, cancer, cardiac diseases (such as viral myocarditis), and skin diseases (such as psoriasis and eczema). R

In this post, we will discuss the many benefits of oxymatrine, its natural sources, and its mechanisms.

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The 27+ Benefits Of Matrine (with Natural Sources And Mechanisms)

Matrine is a very powerful alkaloid that has many neuropharmalogical benefits.

In this post, we will discuss matrine's benefits, natural sources for it, and some of matrine's 195+ mechanisms.

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How GPR84 Senses And Potentiates Inflammation

GPR84 is an inflammation sensor that plays a role in endotoxemia, brain injuries, and obesity.

In this post, we will discuss how to regulate GPR84's function. 

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The 28+ Benefits Of Embelin And Its Natural Sources

Embelin suppresses cancer, combats inflammation, ameliorates autoimmunity, and destroys many infectious agents.

It also has anti-diabetic, anti-obesity, neuroprotective, and cardioprotective protective effects.

In this post, we will discuss the MANY benefits of embelin, its natural sources, and some synergies of embelin.

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What Is Toxin Bioaccumulation? How Biotoxin Accumulation Causes (Reversible) Chronic Dysfunction

Recent evidence suggests that 70–90% of chronic disease is likely related to environmental determinants. 

In this post, we will discuss how biotoxin accumulation may cause chronic illness.

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All About Histamine H3 Receptors (HRH3/HR3): Genetics, Mechanisms, And Antagonists

Is histamine a villain… or really a superhero?

It really depends on which receptor it works on and where it is in the body.

In this post, we will discuss how to use the 3rd histamine receptor to boost cognition, memory, and attention.

We will first discuss how the histamine receptors work.

Then, we will move onto the benefits (and downsides) of blocking Histamine H3 Receptor's (HRH3 or H3R) activity with natural and pharmacological methods.

Lastly, we will discuss the potential benefits of increasing HRH3 with some agonists, HRH3's mechanism of action, and some important HRH3 SNPs.

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PON1: Increase Longevity And Detox Pesticides with 99+ Ways To Increase Paraoxonase 1

Paraoxonase 1 (PON1) is an enzyme that plays a role in most diseases.

In this post, we will discuss how you can use PON1 to improve overall health, longevity, and detox mechanisms.  

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How To Run While Sitting Down: Exercise Mimetics

Exercise Mimetics are novel ways of getting the benefits of exercising, without having to exercise.

In this post, we will discuss the benefits and mechanisms of exercise and some possible ways to replace exercise. 

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How To Inhibit Lipopolysaccharides (LPS), Lipoglycans, and Endotoxins

Recent data suggests that chronically low levels of circulating LPS may be associated with the development of metabolic diseases such as insulin resistance, type 2 diabetes, atherosclerosis and cardiovascular disease. R

In this post, we will discuss how LPS affects the body and how to reverse endotoxemia.

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256+ Ways To Increase Dopamine Naturally (Supplements And Genetics)

Dopamine is extremely important for everyday function and plays a much larger role in the body than just bonding, motivation, cognition, emotion, well-being, and movement.

Unfortunately, our environment today is very good at manipulating and hijacking our dopamine system.

In this post we will discuss, how/why dopamine is produced, how chronic inflammation affects dopamine, what are some quick fixes for dopamine, and what are some long lasting dopamine builders, as well how to avoid losing dopamine. 

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Vasohibin-1 (VASH1) Fights Cancer And Senescence

Vasohibin-1 (VASH1) is an anti-angiogenic protein that may have benefits in cancer and longevity.

In this post, we will discuss conditions associated with VASH1 activity, its benefits, downsides, and ways to change its expression. 

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The 10+ Benefits Of Java Tea (Orthosiphon stamineus)

In this post, we will discuss the benefits of Java (Orthosiphon stamineusis), my experience with Java, and where to get the best form. 

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The 18+ Benefits of Hops (Humulus lupulus)

Have you ever wondered what gave beer its bitter, "hoppy" taste and aroma?

Well the answer is hops. 😋

In this post, we'll be discussing the benefits of hops, how it works on the body, and some non-alcoholic benefits of beer

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The 11+ Benefits Of Maqui (Aristotelia Chilensis)

Maqui (also known as Chilean wineberry, or Chilean blackberry) is a plant native to Chile and Argentina. 

Its berries and leaves have profound bioactive health benefits, which we will discuss in this post.

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The 5+ Benefits Of KB220, KB220Z, and Neuroadaptagen Amino-Acid Therapy

There are many ways to improve dopamine levels in the brain - dopamine-enhancing diets, hyper-oxygenation, toxic heavy metal detoxification, exercise, meditation, yoga, but most notably, balancing brain neurotransmitters utilizing nutraceuticals aka "neuronutrients". 

KB220z (aka KB220 and formerly known as LG9939, Recomposize, Genotrim) is a "neuronutrient" that acts on optimizing glutamatedopamineserotonin, and endorphins in the brain. 

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MANF: What Is It And How To Increase Mesencephalic Astrocyte-Derived Neurotrophic Factor

Mesencephalic astrocyte-derived neurotrophic factor (MANF; also known as ARMET or arginine-rich mutated in early stages of tumor) belongs to the fourth family of neurotrophic factors. 

It plays a huge role in repairing neurons and cells after oxidative stress, and has promising uses for the future in neurodegenerative diseases (such as  Parkinson's Disease).

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The 21+ Benefits Of Beta-Caryophyllene (The Common Cannabinoid)

Beta-Caryophyllene Is A Very Common Cannabinoid

β-caryophyllene is a FDA-approved food additive that can activate the endocannabinoid system. 

It is found in many plants, fragerances, preservatives, additives, and flavoring agents.

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