Recent data suggests that chronically low levels of circulating LPS may be associated with the development of metabolic diseases such as insulin resistance, type 2 diabetes, atherosclerosis and cardiovascular disease. R
In this post, we will discuss how LPS affects the body and how to reverse endotoxemia. Read more
The Actual Dangers of Taking Proton Pump Inhibitors and What You Can Do About It
Proton pump inhibitors are used very commonly by gastroenterologists for anyone with "stomach" issues.
It is probably the first thing they will give a patient before looking further into what the real cause is.
They have serious short-term and long-term downsides and are destroying our brain and our gut. Read more
Histamine intolerance comes from an imbalance of eaten/produced histamine and ability to break it down.
Mast cells, food poisoning, histamine metabolism/liberators and more can exacerbate histamine intolerance. Read more
Have you ever been told to go with your gut feeling? This article describes why.
Changes in the gut microbiota may cause:
Mental health issues (such as anxiety, depression, schizophrenia, and stress) Read more
Clostridium difficile infection
Irritable bowel syndrome (IBS)
Pathogen colonization (i.e. vancomycin-resistant Enterococcus)
Autoimmune and allergic diseases
Obesity and metabolic disorders
Neuropsychiatric disorders such as autism
Secretory Immunoglobulin A (sIgA) is an antibody secreted by mucosal tissue and represents the first line of defense of the GI mucosa.
It is a component of the adaptive immune system, and is an important player in the protection of epithelium.
It is known to have an important impact on the regulation of microbiota composition Read more
During the 80's, LA was believed to be only a deadend waste product from anaerobic exercise.
The idea that lactate is a waste product of the metabolism and a main cause of fatigue, should no longer be considered as an indisputable truth.
This molecule, instead, can be shuttled among cells and, inside the cells, among different organelles, thanks to specific monocarboxylate carriers, and seems to be a fuel for many cells, including neurons, in conditions of oxygen shortage.
It can behave as a signal, eliciting in the cells’ responses which counteract stress, allowing at least an attempt of adaptive responses. Read more