10+ Reasons Why Alcohol Intolerance Happens And How To Build Alcohol Tolerance (Mechanisms And Genetics)

Are you someone who could handle their alcohol until getting sick, then any sort of alcohol in any amount may make you sick?

This is a common problem with those after their immune system has gone haywire.

In this post, I will breakdown and discuss mechanisms behind the loss of tolerance towards alochol

Read more

3 Amazing Benefits Of 3,3′-Diindolylmethane (DIM)

3,3′-diindolylmethane (DIM) is the major bioactive indole in crucifers vegetables, generated upon ingestion and hydrolysis of glucobrassicin.

Read more

X-Linked Inhibitor Of Apoptosis (XIAP) And How To Inhibit XIAP

X-Linked Inhibitor Of Apoptosis (XIAP) has shown to play a role in cancer, longevity, inflammatory resistance, and more.

Read more

Activation And Detoxification 101

In this post, we will discus a brief, technical basic explanation of activation and detoxification - two major mechanisms in oxidative homeostasis.

In the future, I will update this post with more references, a MOA section, genetics, and clearer plans of action. 

Read more

DJ-1/PARK7: How To Revive NRF2 (with 27+ Ways To Increase Protein Deglycase DJ-1)

Protein deglycase DJ-1 (DJ-1), also known as Parkinson disease protein 7 (PARK7) is a master regulator of redox status.

In this post, we will discuss how DJ-1 increases dopamine, enhances mitochondria, and combats most oxidative-stress related diseases. 

Read more

Hormesis: What Doesn't Kill You Makes You Stronger

When you optimize your body and fix all deficiencies, where is there to go next in enhancing your body?

Well there is hormesis, which is a very powerful tool for enhancing all aspects of your life.

Hormesis, if done properly can strengthen metabolism, longevity, and wellbeing as well as protect you from chronic illness in general.

In this post we will discus what hormesis is, how to do it, and what to watch out for so you can do it properly.

Read more

256+ Ways To Increase Dopamine Naturally (Supplements And Genetics)

Dopamine is extremely important for everyday function and plays a much larger role in the body than just bonding, motivation, cognition, emotion, well-being, and movement.

Unfortunately, our environment today is very good at manipulating and hijacking our dopamine system.

In this post we will discuss, how/why dopamine is produced, how chronic inflammation affects dopamine, what are some quick fixes for dopamine, and what are some long lasting dopamine builders, as well how to avoid losing dopamine. 

Read more

Why NRF2 Activation Can Make You More Sick

Recent cancer research has helped us understand how the body detoxes.

By studying upregulated genes in tumorous cells, we were able to find the Nuclear Erythroid 2–Related Factor 2 (NRF2) pathway.

NRF2 is a major transcription factor in detoxing the body and keeping it healthy.

In this post, we will discuss the benefits/downsides of NRF2 activation, as well as why NRF2 may be hurting you more than helping you (and what you can do about it).

Read more

Klotho: Become Smarter And Live Longer With 50+ Ways To Increase Klotho

Klotho may be one of our humans' natural adaptogens by its ability to help regulate cellular stress.

In this post, we will discuss its role in longevity, muscle strength, cancer, cognition, and neurotransmitter balance.

Read more

The 15+ Benefits of Broccoli Sprouts And Sulforaphane (And How To Prepare Them)

Sulforaphane (SFN) is naturally occurring in broccoli sprouts, which has the highest amount of sulforaphane.

Broccoli sprouts contain a particular glucosinolate compound, glucoraphanin, which is found in vacuoles within the cytoplasm of the plant cell. 

The membrane of the plant cells also contain an enzyme, myrosinase, which is walled off from the vacuoles of glucoraphanin. 

Only when the plant cell is ruptured by cutting/chewing,. do the two substances come into contact with each other. 

In the moist environment of the cell, this leads to a chemical reaction wherein the myrosinase converts the glucoraphanin to an isothiocyanate, sulforaphane. 

It is also found in cruciferous veggies, such as brussels spout, cabbage, cauliflower, bok choy, kale, collards, Chinese broccoli, broccoli raab, kohlrabi, mustard, turnip, radish, arugula, and watercress. 

Read more

BDNF: 140+ Natural Ways to Increase Brain Derived Neurotrophic Factor

BDNF is important for longterm memory and helps grow new neurons from neural stem cells (neurogenesis). 

BDNF is important for the development of the brain, sensory nervous system and neural development.

Read more