In this post, we will discuss therapeutic and off-label effects of Cyproheptadine (Periactin), as well as side effects and mechanisms of this drug.Read More
Ecklonia cava is a powerful brown algae that shows promising potential in many metabolic diseases.
In this post, we will discuss the benefits of Ecklonia cava, where to buy it, and its mechanism of action.Read More
Phoenixin is a peptide that regulates reproductive function, behavior, sensory perception, memory retention, cardiovascular health and food intake.Read More
Matrine is a very powerful alkaloid that has many neuropharmalogical benefits.
In this post, we will discuss matrine's benefits, natural sources for it, and some of matrine's 195+ mechanisms.Read More
Embelin suppresses cancer, combats inflammation, ameliorates autoimmunity, and destroys many infectious agents.
It also has anti-diabetic, anti-obesity, neuroprotective, and cardioprotective protective effects.
In this post, we will discuss the MANY benefits of embelin, its natural sources, and some synergies of embelin.Read More
Is histamine a villain… or really a superhero?
It really depends on which receptor it works on and where it is in the body.
In this post, we will discuss how to use the 3rd histamine receptor to boost cognition, memory, and attention.
We will first discuss how the histamine receptors work.
Then, we will move onto the benefits (and downsides) of blocking Histamine H3 Receptor's (HRH3 or H3R) activity with natural and pharmacological methods.
Lastly, we will discuss the potential benefits of increasing HRH3 with some agonists, HRH3's mechanism of action, and some important HRH3 SNPs.Read More
Exercise Mimetics are novel ways of getting the benefits of exercising, without having to exercise.
In this post, we will discuss the benefits and mechanisms of exercise and some possible ways to replace exercise.Read More
The term Humanin (HN) was coined by its discoverer, Professor Nishimoto, to denote the potential of this molecule to restore the “humanity” of patients with Alzheimer’s disease.
Later we have found humanin protects cells from oxidative stress, serum starvation, hypoxia, and other insults as well as also improves cardiovascular disease and Alzheimer's disease.Read More
Calorie Restriction Mimetics (CRMs) are compounds that can induce the same mechanisms as eating less, without having to actually eat less.
In this post, we will discuss how to have your cake (food) and eat it too.Read More
Recent data suggests that chronically low levels of circulating LPS may be associated with the development of metabolic diseases such as insulin resistance, type 2 diabetes, atherosclerosis and cardiovascular disease. R
In this post, we will discuss how LPS affects the body and how to reverse endotoxemia.Read More
Burdock root has been used for centuries (over 3000 years) in China and in traditional Chinese medicine (TCM) for "purifying the blood", but in this post we will discuss the actual ways burdock works on improving the body.Read More
In this post, we will discuss the benefits of chitosan and chitosan derivatives.Read More
There are many ways to improve dopamine levels in the brain - dopamine-enhancing diets, hyper-oxygenation, toxic heavy metal detoxification, exercise, meditation, yoga, but most notably, balancing brain neurotransmitters utilizing nutraceuticals aka "neuronutrients".
KB220z (aka KB220 and formerly known as LG9939, Recomposize, Genotrim) is a "neuronutrient" that acts on optimizing glutamate, dopamine, serotonin, and endorphins in the brain.Read More
Klotho may be one of our humans' natural adaptogens by its ability to help regulate cellular stress.
In this post, we will discuss its role in longevity, muscle strength, cancer, cognition, and neurotransmitter balance.Read More
The Herb With The Strongest Polyphenol Count
Chokeberries (Aronia) are powerful anti-oxidants and anti-inflammatories as they are very high in polyphenols
Deferoxamine is a powerful drug that has potential benefits in restoring neuronal health, especially in those with stroke, Alzheimer's Disease, Parkinson's Disease, spinal cord injury and sleep disorders.
In this post I've gone through it's potential benefits and alternatives to this drug.Read More
Not all artificial sweeteners aka (nonnutritive sweeteners (NNSs) or low-calorie sweeteners (LCS)) are bad.
Use of artificially sweetened foods (ASF) has increased in the past 50 years in the USA and there are clear parallels with changes in the prevalence of being overweight and the rise of obesity. R
Just because something is deemed as "safe" by the FDA, does not make it safe for humans.
In this post, I will break down the effects of artificial sweeteners on the body and give an alternative list to which ones are "safer" or even beneficial.Read More
In 1958, researchers looked at how each unique color affected organisms.
They found out that blue light could change the circadian rhythm of algae, and this was later found out to be true with humans as well.
Our understanding about blue light has increased and I have summarized what the literature shows to date.
Blue light is quite powerful and has the power to reset/disrupt our circadian rhythms, but if used and timed properly it may mitigate diseases like diabetes, obesity, depression, anxiety, bulimia, schizophrenia, dementia, and Parkinson's Disease.
Some of the reasons (more explained below) is because blue light influences hormone secretion, heart rate, alertness, sleep, body temperature, and gene expression.Read More