The 7+ Benefits Of Bladder Mallows (Herissantia)

Bladder Mallows Effect On Allergies And Anxiety

Bladder Mallows is a common herb found in Brazil. 

In this post, we will discuss Bladder Mallows' possible benefits and some alternatives.



Bladder Mallows (BM) aka Herissantia is popularly known as "mela-bode" or "lava-prato". R

It is commonly found in the Brazilian northeast and in folk-lore, it has traditionally been used to treat fevers and the flu. R

BM has a wide array of potential therapeutic benefits acting on allergies, anxiety, infections, the heart, and pain. R


Benefits Of Bladder Mallows

1. May Reduce Asthma And Allergies

BM may be able to reduce the symptoms of asthma. R

For example, it can also reduce allergic inflammation in animal models with chronic asthma. R

BM is also able to reduce mucus from building up in the lungs. R

BM also has anti-allergy effectsR

2. May Decrease Anxiety

In humans, anxiety is very common among asthmatics. R R R R

In animal models with asthma, BM was able to their reduce anxiety. R

3. Has Anti-Inflammatory Properties

Similarly to its ability to reduce asthma and allergy symptoms, BM has anti-inflammatory properties. R

For example, in animals models with carrageenan-induced swelling, BM is able to reduce inflammation by modulating the immune system. R

4. May Protect The Gut

Similarly to its regulation of mucus in the lungs, BM can regulate mucus in the gut as well, providing anti-ulcer properties. R

For example, BM is able to protect reduce gastric lesions in animal models given excessive alcohol and prevent diarrhea in animal models given castor oil. R

5. Makes Some Antibiotics More Effective

BM has shown anti-microbial effects against:

  • Escherichia coli R
  • Listeria monocytogenes R
  • Shigella flexineri R
  • Shigella sonnei R
  • Salmonella R
  • Yerisinea entercrocololytica R

When BM is combined with antibiotics, it can make those antibiotics more effectiveR

For example, in one study BM has shown to be very effective (128-fold) against bacterial resistance of Staphylococcus aureus when combined with norfloxacin (16-fold), ciprofloxacin (16-fold), lomefloxacin (four-fold) and ofloxacin (two-fold). R

Other studies have shown similar results. R

BM also has anti-fungal effects against Paracoccidioides brasiliensis. R

6. May Protect The Heart

BM may improve the vascular systemR

It may also decrease levels of high blood pressure. R

7. May Help With Pain

BM may reduce pain via regulation of glutamate (independent of the opioid system). R R

Bladder Mallows Alternatives


The best way to get the benefits of Bladder Mallows is probably by taking some of its bioactive components:


In mice, BM has low toxicity showing no ill effect even at 2000 mg/kg. R

No clinical trials have been performed for BM.

Mechanism Of Action


  • Decreases IgE R
  • Decreases IL-1beta R
  • Decreases IL-6 R
  • Decreases IL‐13 R
  • Decreases Nitric Oxide R
  • Decreases TNF-alpha R


  • Herissantia is part of the Malvaceae/mallows family (with over 244 genera and 4225 known species) and contains polyoxygen flavonoids, triterpenes, steroid, phenolic compounds and flavonoid glycosides such as kaempherol, lespedin, tiliroside, 5-hydroxyauranetin, araneosol, calycopterin, and sarothrin. R R R
  • In the lungs of rodents, HT can reduce immunoglobulins (IgE). R
  • HT reduces Interluekin-13 (IL‐13), which induces production of mucus by lung epithelial goblet cells, acting on their proliferation, differentiation, and secretory function, and it switches to IgE by B cells. R
  • HT also reduces CD3+ T‐lymphocytes and decreases percentage of B220+ cells (B cells) in the lungs. R

More Research

  • H. crispa has a low IC50 value (1.63 ± 0.86 mg/mL) compared to ascorbic acid in the TEAC assay. R