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DetoxActivation And Detoxification 101
In this post, we will discus a brief, technical basic explanation of activation and detoxification - two major mechanisms in oxidative homeostasis.In the future, I will update this post with more…
DietRecipes for NRF2
In this post, we will go over some recipes that highly activate NRF2, the major detox pathway.
Sun & LightHow Sunlight Fights Infections: The Real Mechanisms Behind Light And Immune Defense
Sunlight has measurable antimicrobial and immune-modulating effects, but the mechanisms are more specific and interesting than the popular framing of "oxidizing the blood."
SupplementsThe 16+ Benefits Of Spilanthes, Spilanthol, And Alkylamides
Spilanthes is a genus of plants that have major potential as an aphrodisiac and anti-aging tool.In this post, we will discuss spilanthes, the benefits of its bioactive components, and where to get it.
DietNSAIDs Alternative Recipes
Here are some ingredients that help with inflammation and may be used as alternative to NSAIDs.
SupplementsThe 49+ Benefits of THC, CBD, and The Endocannabinoid System
Medical marijuana and legalization have been a hot topics recently. I wanted to cover the plethora of benefits of the endocannabinoid system.Disclaimer: I made sure to only work on this post while…
VascularMicroplastics And Your Health: Where They Accumulate, What The Evidence Shows, And How To Lower Exposure
Micro- and nanoplastics are now measurable in human blood, arterial plaque, testes, and brain tissue. Here is what the strongest human evidence actually shows, how the particles connect to gut and…
Supplements9 Benefits Of Vitamin C (Ascorbic Acid): Collagen, Immunity, And The Redox Buffer Humans Can't Make
Vitamin C is the electron-donating cofactor behind collagen synthesis, neutrophil immune function, and iron absorption, and humans lost the gene to make it on their own roughly 50 to 65 million years…
SupplementsPMDD: The Neurobiology Behind Premenstrual Dysphoric Disorder And How To Address It
Premenstrual dysphoric disorder (PMDD) is a severe cyclic mood disorder with a distinct neurobiological basis involving allopregnanolone, GABA receptor sensitivity, serotonin, and a frequently…
SkinPsoriasis As A Neuroimmune Disease: Neurogenic Inflammation, NGF, And Why Cutting A Nerve Can Clear A Plaque
Psoriasis is driven by nerves as much as immunity, and cutting the nerve to a plaque can clear it. Here is the neuroimmune model of psoriasis.
SupplementsMolecular Hydrogen (H2): Selective Antioxidant, Gut, And Fatigue
The selective antioxidant story for H2 is more contested than it looks, because the reaction rate with hydroxyl radical may be too slow to explain the effects. Here is the signaling alternative, how…
DrugsUnderstanding Proton Pump Inhibitors (Part 3)
Last week, I posted about a type of common drug called NSAIDs and their dangerous side effects. This week, we’re going to look at another popular category of drugs: Proton Pump Inhibitors or…
PeptidesAdropin: A Predictor of Heart Disease
Preptin, adropin and irisin are three co-workers in the regulation of energy homeostasis. Adropin is derived from the Latin roots “aduro” [to set fire to] and “pinquis” [fats or oils]. It was first…
GeneticsIron Overload and Ferritin Dysregulation: The HFE Gene, Hemochromatosis, and Why High Ferritin Isn't Always Inflammation
Serum ferritin can rise from real iron overload or from inflammation alone, and telling them apart requires the HFE gene, transferrin saturation, and the Fenton reaction that makes stored iron…
MindsetThe Reason Why Tony Robbins Has SO MUCH ENERGY
Tony Robbins is a great guy. Hell, he's "OUTSTANDING". He's changed millions of people's lives and he changed mine. Using his confidence he has been able to influence so many people. During these…
SupplementsApigenin: Benefits, CD38/NAD+, Sleep, And The Chamomile Connection
Apigenin is the chamomile flavone that calms the brain at the GABA-A receptor and raises NAD+ by inhibiting CD38, with strong mechanisms in a dish but a serious oral bioavailability problem of…
Alzheimer'sThe 8+ Benefits Of J147: A Potent Curcumin Derivative (And How To Make T-006)
Unlike the current drugs approved for Alzheimer's Disease, J147 is neither an acetylcholinesterase inhibitor nor a phosphodiesterase inhibitor, yet it enhances cognition with a short-term…
Mitochondria TrendingNAD+, NADH, NADP+, And NADPH: The Redox Molecules Running Every Cell You Have
These four molecules are the reason your cells can make energy, repair DNA, neutralize free radicals, synthesize fat, and stay alive. NAD+/NADH operates in catabolic metabolism, while NADP+/NADPH…