Abstract

SUMMARY:

The human body functions as a SRCS, adapting to stress through mechanisms like AREs. However, overload from various stressors can lead to JD, causing issues like TCLS and MSS, disrupting vasoadaptation, fluidity, and leading to inflammation, auto-intoxication, and immune system suppression. Addressing dysfunctions at multiple levels is necessary to restore the SRCS homeostasis and complete WHCs.