100+ Scientifically Proven Ways to Lose Weight That Don't Include exercise

Lose Weight with SCIENCE! #75 Is My Favorite 😊


Disclaimer: Exercise and diet are beneficial for you in many ways.
This is NOT a replacement for exercise and diet.
Also some of these studies are small and some are done only on animals.
It is UP TO YOU to asses which of these are beneficial or harmful for you.
Obviously, things like "illness and MDMA" are probably things you'd want to stay away from.

100 Ways to Lose Weight


  1. Exercise - Somewhat effective 😂 - I swear that's the only one on this list that is exercise. R
  2. Yoga - Obese patients lost weight. R
  3. Intranasal Leptin (or Myalept/Metreleptin) - Intranasal leptin has been demonstrated to reduce appetite and induce weight loss. R R
  4. Intranasal Insulin - INI administration for 8 weeks reduced body fat in normal-weight men, not women. R R
  5. Bifidobacterium B. L66-5 - Bifidobacterium aided in weight loss. R
  6. Lactobacillus gasseri - It reduced weight and weight gain. R
  7. Lactobacillus rhamnosus - It also reduced weight and weight gain. R
  8. L. rhamnosus + Bifidobacterium lactis - This combo reduced weight and stopped weight gain. R
  9. Lactobacillus gasseri - In diet obese mice, it helped them lose weight by reducing insulin levels. R
  10. Ketogenic Diet- It significantly reduced the body weight and body mass index of the patients. R
  11. Caloric Restriction - Also reduced weight and inflammation (hs-CRP, SAA and IL-6). R 
  12. Intermittent Fasting - Induces weight loss and helps maintain weight loss. R
  13. Butyrate - Butyrate caused obese mice to lose ~10% of their original body weight and fat mass. R
  14. Don't Eat After 8pm - Increased the risk of obesity (unrelated to sleep time and duration). R
  15. Reduce Stress - Stress is associated with high BMI. R
  16. Fish - It decreases leptin, which is high in obese patients. R
  17. High Protein Diet - Increased fat burning and reduced appetite. R R
  18. Chew Gum - Chewing gum (for at least 45min) suppressed appetite and cravings, while promoting fullness. R
  19. CCK Injection - Enhances reduction of body weight. R
  20. Caffeine - High caffeine is associated with weight loss by thermogenesis, oxidation, and increasing leptin. R
  21. Bitter Orange - It increased resting metabolic rate, energy expenditure, and increased weight loss. R
  22. Oleic Acid - It is found in olive oil and excites neurons to promote weight loss. R
  23. MCT Oil - Supplementation resulted in lower body weight than did olive oil. R
  24. Metformin - It induced modest weight loss in overweight and obese individuals at risk for diabetes. R
  25. Nicotine - Reduces appetite and alters feeding patterns resulting in reduced body weight. R
  26. Sauna - Induced wight loss in overweight people. R
  27. Apple Cider Vinegar - It reduces appetite. R
  28. Low-dose Growth Hormone - Along with reduced calories, it increased fat loss muscle gain. R
  29. Stay away from MSG - It increases appetite. R
  30. Glycemic Control - Hypoglycemia increases appetite (obviously) R
  31. Eating Slowly - Maximized satiation and reduced energy intake within meals. R
  32. Drinking Water - 2 liters of water per day helped people burn 96 calories extra. R
  33. Drinking Hydrogen Water - Helps burn brown fat. R
  34. NGF - It reduces appetite and prevents weight gain. R
  35. CNTF - It can overcome leptin resistance in order to reduce body weight. R
  36. BDNF - It induces appetite suppression and weight loss. R 
  37. GDNF - It increased energy expenditure and may be useful for the treatment or prevention of obesity. R
  38. Oxytocin - It decreased hunger. R
  39. Norepinephrine (or being anxious) - It suppressed hunger. R
  40. Get Cold Exposure - It increases TRH (which is an appetite suppressant). R
  41. Increase Sleep - Short sleep is associated with weight gain. R
  42. Melatonin - Improves sleep and contributes to body weight reduction. R
  43. Get Sun - It increases MSH which induces BDNF (that suppresses appetite and weight loss). R
  44. Bright Light - Red and green light increased leptin and decreased ghrelin. R
  45. Decreasing Prolonging Light - Prolonged exposure increased obesity and appetite. R
  46. Reduce Blue Light at Night - Blue light can cause weight gain. R
  47. Vitamin D- Weight loss is associated with an increase in vitamin D. R R
  48. Decrease Alcohol Intake - Alcohol intake may be a risk factor for obesity in some individuals. R
  49. Vagus Nerve Stimulation - The more severe the obesity, the greater the weight loss. R
  50. Increase Orexin - Orexin-A treatment induces weight loss in rats. R


  1. Circadian Rhythm Control - Shift-workers had a higher chance of obesity. R
  2. EGCG - It inhibits MAO-B, resulting in weight loss. R
  3. Green Tea - It helps you burn more calories. R
  4. HMG - It decreased fat mass while increasing lean mass. R
  5. Berberine - In 12 weeks obese people lost an average of 5 pounds. R
  6. Forskolin - Men had a decrease in body fat. Women's body fat was mitigated. R R
  7. CLA - Subjects lost 3lbs compared to placebo. R
  8. Creatine - In combination with CLA  lead to greater increases in fat-free mass and losses of fat mass. R
  9. Testosterone - Worked in men that were low in T. R
  10. Estrogen - Worked in women that were low in E. R
  11. Get Off Birth Control - They will increase fat and decrease muscle. R
  12. Mucuna - By manipulating dopamine levels altered eating behavior. R
  13. Amphetamines - And can make you practically anorexic. R
  14. MAOIs - By raising catecholamines. R
  15. Sibutramine - It increased serotonin and dopamine, which resulted in weight loss. R
  16. I3C - It decreased adipogenesis and inflammation. R
  17. Blueberry Peel Extracts - BPE reduced body weight gain and inhibited fat accumulation. R
  18. Carvacrol - Supplementation prevents diet-induced obesity by regulating brown fat. R
  19. Rhodiola - In combination with bitter orange, it increased noradrenaline and reduced fat. R
  20. Curcumin - It inhibits adipocyte differentiation. R
  21. Apple Polyphenols - It protected against body weight gain and fat deposition. R
  22. Milk Thistle - It lowers adipogenesis (fat cell production). R
  23. Lipoic Acid - It helped reduce food intake and enhanced energy expenditure. R
  24. L-Arginine & L-Citruline - It reduced unfavorable fat. R
  25. Dark Chocolate - It decreased the expression of genes involved in fatty acid synthesis. R
  26. Histidine - It reduced BMI and fat mass. R
  27. Hops - In animal models being fed a high-fat diet with hop extract, XN was able to prevent weight gainR
  28. Garcinia - Garcinia extracts/HCA can cause short-term weight loss. R
  29. Meratrim - Supplementation resulted in a greater degree of weight loss than placebo over 8 weeks. R
  30. Cissus Quadrangularis - Regardless of diet, there was significant reductions in weight and obesity. R
  31. Glucomannan - It induced body weight reduction in healthy overweight subjects. R
  32. Resistant Starch -It increased fat oxidation and reduced fat storage in adipocytes. R
  33. Capsaicin - Consumption of 2.56 mg capsaicin per meal promoted fat oxidation. R
  34. Quercitin - It decreased high-fat diet induced body weight gain. R
  35. Eat Avocados -  Body weight, BMI, and waist circumference were significantly lower. R
  36. Cut Out TV Time - Viewing TV might increase the likelihood of being overweight. R
  37. Stand More - weight maintenance following weight loss is associated with avoiding sedentary behavior. R
  38. Dancing - It decrease decreased weight, fat, and BMI. R
  39. LLLT - It produced significant girth loss sustained over repeated treatments in spot fat. R
  40. Illness - It is commonly associated with weight loss. R
  41. Increase Fiber - It worked better in obese patients. R
  42. Liquid Diet - It in enhanced satiety, thus eating less. R
  43. Eating Eggs - Instead of eating bagels for breakfast, eating eggs helps obese women decrease hunger. R
  44. Increase Nitric Oxide - It stimulates glucose and fatty acid breakdown. R
  45. Mindfulness Meditation - It effectively decreases binge eating and emotional eating. R R
  46. Chronic MDMA Use - It can lead to weight loss. R
  47. LSD - Weight loss over the 8 weeks was 2.2 kg. R
  48. Cocaine - Its use suppresses appetite. R
  49. Radiation Therapy - By inducing dehydration. R
  50. Chemotherapy - Weight loss happens and is worse for outcome. Weight gain is better. R


  1. BDA-410 - It reduces body weight and fat content by enhancing lipolysis. R
  2. Nonivamide - It helps to support to maintain a healthy body composition. R
  3. Maslinic acid - It affected the weight of volunteers with mild knee joint pain. R
  4. Reducing Inflammation - Inflammation halts the fat burning process. R
  5. Tachykinin - It stimulates serotonin pathways to burn fat. R
  6. Ghrelin/Mk-677/Ibutamoren - After 8-14 days of use, patients had significant weight loss. R
  7. DNP (Dinitrophenol) - It cause rapid loss of weight (but has many side effects, like death). R
  8. Irisin - It stimulates white fat to turn into brown fat via PGC1α. R
  9. Amylin - It induces feeling of satiety and enhances leptin. R
  10. Spirulina - Intake of 2.8 g of spirulina thrice a day results in a significant reduction in body weight. R
  11. Swallowable Gastric Balloon - This works as a replacement for gastric bypass surgery. R
  12. Damiana - In YGD, it helps reduce food intake, slow gastric movement, and reduce body weight. R
  13. Avoid Arsenic - It decreases birth weight but increases adult weight gain. R
  14. Avoid Glyphosate and Roundup - They increase obesity, partly through their estrogenic properties. R
  15. Avoid Estrogenics and Birth Control - They activate PPARgamma to increase weight gain. R R
  16. Avoid Artificial Sweeteners - They alter tastebud receptors, insulin in the body, and increase weight gain. R
  17. NRF2 activation - It increases mitochondrial output thus decreasing white adipose tissue (fat). R R
  18. Cupping - Women receiving dry cupping had decreased amounts of cellulite. R
  19. Shinrin Yoku (Forest Bathing) - Green light decreases the rate of obesity. R
  20. Maqui - It can inhibit adipogenesis (growth of fat cells) and inflammation. R
  21. KB220z - It can help with compulsive eating and weight loss. R R
  22. Aronia - It helps keep stable blood sugar and lose visceral fat. R
  23. Deferoxamine - In mice that were obese, DFO helped reduce weight grain. R
  24. Amantadine - It was able to prevent the weight gain from antipsychotic use. R
  25. XSLJZD - By increasing ghrelin, it can promote fat burning. R
  26. Tian Ma/Gastrodin - It potentiates leptin signaling, thus decreasing eating. R
  27. Amentoflavone - It inhibits fatty acid synthase, thus preventing obesity. R
  28. Huang Bai - It can inhibit the formation of fat, decrease weight gain, and suppress hungerR
  29. Zizihpus Jujube - It reduces inflammation in fat, inhibiting more fat accumulation. R
  30. Beta-Caryophyllene - It reduces formation of new fat cells R R
  31. Dopamine - increases perceived effort to workout and reduces willingness to eatR R

More Research

  • Avoid a Chain Reaction - One mistake could lead to more and you want to break this pattern. R
  • Weight Related Problems have been linked to type 2 diabetes, kidney disease, fatty liver, heart disease, stroke, and sleep apnea. R
  • Up to 76 percent of the world's population is overfat. R