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PeptidesAll About Phoenixin: Pros And Cons Of Phoenixin And GPR173
Phoenixin is a peptide that regulates reproductive function, behavior, sensory perception, memory retention, cardiovascular health and food intake.
EpigeneticsThe Epigenetics Of Attachment Style: A Gene-By-Gene Map
A gene-by-gene map of the biology people invoke for attachment style, with an honest case for and against each pathway. The few genes with real evidence are epigenetic, and the long list of candidate…
LongevityBring Out Your Dead… I’m Not Dead Yet (8+ Benefits Of Reducing Indy)
Reducing the expression of the gene Indy has shown to improve the health and longevity of humans, flies, mice, and worms. In this post, we will discuss the benefits of lower Indy levels and how to…
SupplementsThe 27+ Benefits Of Burdock (Arctium lappa)
Burdock root has been used for centuries (over 3000 years) in China and in traditional Chinese medicine (TCM) for "purifying the blood", but in this post we will discuss the actual ways burdock works…
VascularApoB And Lp(a): The Cardiovascular Markers That Matter More Than LDL Cholesterol
ApoB and lipoprotein(a) predict heart attacks better than a standard LDL cholesterol number, and most people never test either one. Here is what they are, why they beat LDL-C, how they damage…
Supplements8+ Benefits of PQQ (Pyrroloquinoline Quinone) For Mitochondrial Biogenesis
PQQ is sold as a way to grow new mitochondria, and the marketing has run ahead of the human data. Here is what the mechanism actually supports, where it shows up in food, how to dose it, how it pairs…
SupplementsPMDD: The Neurobiology Behind Premenstrual Dysphoric Disorder And How To Address It
Premenstrual dysphoric disorder (PMDD) is a severe cyclic mood disorder with a distinct neurobiological basis involving allopregnanolone, GABA receptor sensitivity, serotonin, and a frequently…
ME/CFS8 Benefits Of Oxaloacetate: The NAD+/NADH Ratio, TCA Anaplerosis, And The Fatigue Evidence
Oxaloacetate is a four-carbon TCA-cycle intermediate that behaves as a caloric-restriction mimetic, shifting the NAD+/NADH ratio the way fasting does. Here is what the ME/CFS and long COVID fatigue…
DietSystemic Candida Overgrowth: Mechanisms, Testing, And Treatment Beyond The Yeast-Free Diet
Systemic Candida overgrowth happens when a normally harmless gut yeast shifts shape into invasive hyphae, builds a biofilm fortress, and leaks inflammatory debris into the rest of the body.
Alzheimer'sReverse Alzheimer's With The Bredesen Protocol - ReCODE
This is a simple explanation of the Bredesen Protocol, also known as ReCODE. It is a cutting edge protocol to reverse Alzheimer's and has been successful for over 250 patients.It includes the…
SupplementsThe 6+ Benefits of Chaga Mushroom (Inonotus obliquus): Antioxidants, Immunity, and the Oxalate Caution
Chaga inherits its most cited anticancer compound from the birch trees it parasitizes, and its polysaccharides drive real but preclinical antioxidant and immune effects. Two cautions most articles…
SupplementsParvalbumin: Why You Can't Supplement For Fish
In this post, we will discuss what parvalbumin is, how it plays a role in chronic illnesses, and what you can do to increase it.
MindsetCoregulation And Attachment Style: How Your Early Nervous System Wiring Shapes Your Biology
Attachment style is not simply a psychological preference but a physiological set-point that determines how efficiently your autonomic nervous system coregulates with other people. This post covers…
SupplementsCurcumin: Anti-Inflammatory Mechanisms, Absorption, And Safety
Curcumin has thousands of papers behind it and a serious credibility problem, because it interferes with the very assays used to study it. Here is the honest read: which delivery systems actually…
DepressionHow Retinoids Gave Me Panic Attacks And Depression
This post is in a completely different style/language than other posts I've done. As a blogger, what do you do after a breakup?Write about why it happened, of course!
MitochondriaHow Chronic Fluoride Can Damage Mitochondria And The Gut Biome
Fluoride is a trace element, but it is found in our daily exposure more than a "trace". In small amounts, it appears to be okay. The problems with fluoride appear to be in chronic use of it over long…
SupplementsL-Citrulline vs L-Arginine For Nitric Oxide: A Safety-First Comparison
L-citrulline and L-arginine are both promoted as nitric oxide boosters, but they travel fundamentally different metabolic paths. This post compares them, explains why arginine is riskier in the JD…
Parkinson'sCDNF: What It Is and How To Increase Cerebral Dopamine Neurotrophic Factor
Cerebral Dopamine Neurotropic Factor (CDNF) is a newly discovered (and very powerful) way to regrow damaged dopaminergic neurons. It has shown have anti-inflammatory effects that are very beneficial…